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Western Blot (WB) (GABPB1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GABPB1 antibody detected the GABPB1 protein (arrow).)

Rabbit GABPB1 Polyclonal Antibody | anti-GABPB1 antibody

GABPB1 Antibody (C-term)

Gene Names
GABPB1; E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; E4TF1-47; E4TF1-53
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GABPB1; Polyclonal Antibody; GABPB1 Antibody (C-term); GA-binding protein subunit beta-1; GABP subunit beta-1; GABPB-1; GABP subunit beta-2; GABPB-2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53; E4TF1B; GABPB; GABPB2; anti-GABPB1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GABPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the C-terminal region of human GABPB1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
337-365
Sequence Length
348
Applicable Applications for anti-GABPB1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(GABPB1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GABPB1 antibody detected the GABPB1 protein (arrow).)

Western Blot (WB) (GABPB1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GABPB1 antibody detected the GABPB1 protein (arrow).)
Related Product Information for anti-GABPB1 antibody
This gene encodes the GA-binding protein transcription
factor, beta subunit. This protein forms a tetrameric complex with
the alpha subunit, and stimulates transcription of target genes.
The encoded protein may be involved in activation of cytochrome
oxidase expression and nuclear control of mitochondrial function.
The crystal structure of a similar protein in mouse has been
resolved as a ternary protein complex. Multiple transcript variants
encoding distinct isoforms have been identified for this gene.
References
Eynon, N., et al. Physiol. Genomics 41(1):78-81(2010)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Vercauteren, K., et al. J. Biol. Chem. 283(18):12102-12111(2008)
Collins, P.J., et al. PLoS Genet. 3 (11), E208 (2007) :

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42483
NCBI Official Full Name
GA-binding protein subunit beta-1 isoform gamma 1
NCBI Official Synonym Full Names
GA binding protein transcription factor, beta subunit 1
NCBI Official Symbol
GABPB1
NCBI Official Synonym Symbols
E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; E4TF1-47; E4TF1-53
NCBI Protein Information
GA-binding protein subunit beta-1
UniProt Protein Name
GA-binding protein subunit beta-1
Protein Family
UniProt Gene Name
GABPB1
UniProt Synonym Gene Names
E4TF1B; GABPB; GABPB2; GABP subunit beta-1; GABPB-1; GABPB-2
UniProt Entry Name
GABP1_HUMAN

NCBI Description

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

GABPB1: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; protein heterodimerization activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; transcription, DNA-dependent; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter

Research Articles on GABPB1

Similar Products

Product Notes

The GABPB1 gabpb1 (Catalog #AAA9213167) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 337-365. The GABPB1 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's GABPB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GABPB1 gabpb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABPB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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