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Western Blot (WB) (Western Blot analysis of GABAA Rbeta2 polyclonal antibody)

Rabbit anti-Human, Mouse GABAA Rbeta2 Polyclonal Antibody | anti-GABAA antibody

GABAA Rbeta2 Polyclonal Antibody

Gene Names
GABRB2; ICEE2
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
GABAA Rbeta2; Polyclonal Antibody; GABAA Rbeta2 Polyclonal Antibody; Gamma-aminobutyric acid receptor subunit beta-2; GABA(A) receptor subunit beta-2; GABRB2; anti-GABAA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
GABAA Rbeta2 polyclonal antibody detects endogenous levels of GABAA Rbeta2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
512
Applicable Applications for anti-GABAA antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant full length Human GABAA Rbeta2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of GABAA Rbeta2 polyclonal antibody)

Western Blot (WB) (Western Blot analysis of GABAA Rbeta2 polyclonal antibody)
Related Product Information for anti-GABAA antibody
Gamma-aminobutyric acid type A (GABAA) receptors are members of the neurotransmitter ligand-gated ion channels that mediate neuronal inhibition on binding GABA. The effects of GABA on GABAA receptors are modulated by a range of therapeutically important drugs, including barbiturates, anaesthetics and benzodiazepines.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 59kDa
NCBI Official Full Name
Gamma-aminobutyric acid receptor subunit beta-2
NCBI Official Synonym Full Names
gamma-aminobutyric acid type A receptor subunit beta2
NCBI Official Symbol
GABRB2
NCBI Official Synonym Symbols
ICEE2
NCBI Protein Information
gamma-aminobutyric acid receptor subunit beta-2
UniProt Protein Name
Gamma-aminobutyric acid receptor subunit beta-2
UniProt Gene Name
GABRB2
UniProt Entry Name
GBRB2_HUMAN

NCBI Description

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]

Uniprot Description

Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.

Research Articles on GABAA

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Product Notes

The GABAA gabrb2 (Catalog #AAA3009162) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GABAA Rbeta2 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GABAA Rbeta2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the GABAA gabrb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABAA Rbeta2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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