Immunohistochemistry (IHC)
(Immunohistochemical staining of normal human brain tissue using P2Y13 antibody at 15 ug/ml)
Rabbit anti-Human G-Protein Coupled Receptor 94 Polyclonal Antibody | anti-P2RY13 antibody
G-Protein Coupled Receptor 94
Immunohistochemistry (IHC)
(Immunohistochemical staining of normal human brain tissue using P2Y13 antibody at 15 ug/ml)
Immunohistochemistry (IHC)
(Immunohistochemical staining of normal human brain tissue using P2Y13 antibody at 15 ug/ml)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]
Uniprot Description
Function: Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. Ref.2
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined.
Miscellaneous: Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Sequence caution: The sequence AAH29363.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.The sequence AAH41116.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence BAG36024.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on P2RY13
Similar Products
Product Notes
The P2RY13 p2ry13 (Catalog #AAA395785) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The G-Protein Coupled Receptor 94 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's G-Protein Coupled Receptor 94 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the P2RY13 p2ry13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "G-Protein Coupled Receptor 94, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
