Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FOXB1 Polyclonal Antibody at dilution 1:30)
Rabbit FOXB1 Polyclonal Antibody | anti-FOXB1 antibody
FOXB1 Polyclonal Antibody
Gene Names
FOXB1; FKH5; HFKH-5
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
FOXB1; Polyclonal Antibody; FOXB1 Polyclonal Antibody; FKH5; HFKH-5; anti-FOXB1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.2mg/mL (varies by lot)
Sequence Length
325
Applicable Applications for anti-FOXB1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human FOXB1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FOXB1 Polyclonal Antibody at dilution 1:30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FOXB1 Polyclonal Antibody at dilution 1:30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FOXB1 Polyclonal Antibody at dilution 1:30)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FOXB1 Polyclonal Antibody at dilution 1:30)
Related Product Information for anti-FOXB1 antibody
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,978 Da
NCBI Official Full Name
Forkhead box protein B1
NCBI Official Synonym Full Names
forkhead box B1
NCBI Official Symbol
FOXB1
NCBI Official Synonym Symbols
FKH5; HFKH-5
NCBI Protein Information
forkhead box protein B1; transcription factor FKH-5
UniProt Protein Name
Forkhead box protein B1
Protein Family
UniProt Gene Name
FOXB1
UniProt Synonym Gene Names
FKH5
UniProt Entry Name
FOXB1_HUMAN
Uniprot Description
FOXB1:
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component: nucleus
Molecular Function: sequence-specific DNA binding
Biological Process: lactation; transcription from RNA polymerase II promoter; floor plate development; somitogenesis; thalamus development; regulation of transcription from RNA polymerase II promoter; axon target recognition; spinal cord development; mammilary body development; midbrain development; visual learning; negative regulation of neuron apoptosis; hypothalamus cell migration; urogenital system development; telencephalon cell migration
Similar Products
Product Notes
The FOXB1 foxb1 (Catalog #AAA2526780) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOXB1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FOXB1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the FOXB1 foxb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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