Chicken anti-Human, Mouse Fox3 Polyclonal Antibody
Fox3 (Fox-3, Fox-1 Homolog C, Hexaribonucleotide-binding Protein 3, Hrnbp3, Neuronal Nuclei, NeuN, RNA Binding Protein Fox-1 Homolog 3, RBFOX3)
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunocytochemistry
Purity
Affinity PurifiedAffinity Purified
Synonyms
Fox3; Polyclonal Antibody; Fox3 (Fox-3; Fox-1 Homolog C; Hexaribonucleotide-binding Protein 3; Hrnbp3; Neuronal Nuclei; NeuN; RNA Binding Protein Fox-1 Homolog 3; RBFOX3); Anti -Fox3 (Fox-3; anti-Fox3 antibody
Host
Chicken
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgY
Specificity
Recognizes FOX3. Species Crossreactivity: human and mouse.
Purity/Purification
Affinity Purified
Affinity Purified
Affinity Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Applicable Applications for anti-Fox3 antibody
Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Application Notes
Suitable for use in Immunohistochemistry and Immunocytochemistry.
Dilution: Immunohistochemistry: 1:1000
Dilution: Immunohistochemistry: 1:1000
Immunogen
Synthetic peptide corresponding to the Fox-3 gene product, shared between the human (NP_001076044) and mouse (NP_001020102) sequences, conjugated to KLH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-Fox3 antibody
Fox3 is one of a family of 3 mammalian Fox homologues. Fox was discovered in C. elegans as a gene involved in sex determination, and the name Fox is an acronym of "Feminizing locus on X". The Fox protein and its 3 mammalian homologues are all about 46kD proteins each of which includes a central highly conserved RRM type RNA recognition motif, which corresponds to a small ~70aa structure consisting of 4 beta strands and two alpha-helices. An alternate name for Fox 3 is hexaribonucleotide binding protein 3, and these proteins are believed to have a role in the regulation of mRNA splicing.
Much interest has focused on Fox3 as this protein corresponds to NeuN, a neuronal nuclear antigen. NeuN antibody has become very widely used as a robust marker of neurons and neuronal stem cells. Fox3 is therefore a protein which has a funciton in RNA splicing and is expressed heavily and specifically in neuronal nuclei.
Much interest has focused on Fox3 as this protein corresponds to NeuN, a neuronal nuclear antigen. NeuN antibody has become very widely used as a robust marker of neurons and neuronal stem cells. Fox3 is therefore a protein which has a funciton in RNA splicing and is expressed heavily and specifically in neuronal nuclei.
Product Categories/Family for anti-Fox3 antibody
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
42,833 Da
NCBI Official Full Name
Fox3 peroxisomal 3-oxoacyl CoA thiolase
UniProt Protein Name
Fox3 peroxisomal 3-oxoacyl CoA thiolase
Protein Family
UniProt Entry Name
H8X6E5_CANO9
Uniprot Description
Sequence similarities: Belongs to the thiolase family. RuleBase RU003557
Similar Products
Product Notes
The Fox3 (Catalog #AAA645197) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The Fox3 (Fox-3, Fox-1 Homolog C, Hexaribonucleotide-binding Protein 3, Hrnbp3, Neuronal Nuclei, NeuN, RNA Binding Protein Fox-1 Homolog 3, RBFOX3) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Fox3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunocytochemistry (ICC). Suitable for use in Immunohistochemistry and Immunocytochemistry. Dilution: Immunohistochemistry: 1:1000. Researchers should empirically determine the suitability of the Fox3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fox3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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