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Western Blot (WB) (Western blot analysis of FosB expression in PMA treated COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.)

Rabbit anti-Human, Mouse FOS B Polyclonal Antibody | anti-FOS B antibody

FOS B antibody

Gene Names
FOSB; AP-1; G0S3; GOS3; GOSB
Reactivity
Human, Mouse
Applications
Western Blot, Immunofluorescence, Immunocytochemistry
Purity
Immunogen affinity purified
Synonyms
FOS B; Polyclonal Antibody; FOS B antibody; G0/G1 switch regulatory protein 3; G0S3; Protein fosB; anti-FOS B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
FosB Antibody detects endogenous levels of total FosB
Purity/Purification
Immunogen affinity purified
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
302
Applicable Applications for anti-FOS B antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Immunogen Type
Peptide
Immunogen Description
A synthesized peptide derived from human FosB
Target Name
FOS B
Preparation and Storage
Store at -20 degree C/1 year

Western Blot (WB)

(Western blot analysis of FosB expression in PMA treated COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.)

Western Blot (WB) (Western blot analysis of FosB expression in PMA treated COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.)
Product Categories/Family for anti-FOS B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,978 Da
NCBI Official Full Name
protein fosB isoform 2
NCBI Official Synonym Full Names
FBJ murine osteosarcoma viral oncogene homolog B
NCBI Official Symbol
FOSB
NCBI Official Synonym Symbols
AP-1; G0S3; GOS3; GOSB
NCBI Protein Information
protein fosB
UniProt Protein Name
Protein fosB
UniProt Gene Name
FOSB
UniProt Synonym Gene Names
G0S3
UniProt Entry Name
FOSB_HUMAN

NCBI Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

FosB: FosB interacts with Jun proteins enhancing their DNA binding activity. Heterodimer. Belongs to the bZIP family. Fos subfamily.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: nucleus

Molecular Function: DNA binding; sequence-specific DNA binding; double-stranded DNA binding; transcription factor activity; transcription factor binding

Biological Process: transcription from RNA polymerase II promoter; response to drug; response to cAMP; response to mechanical stimulus; response to morphine; female pregnancy; negative regulation of transcription from RNA polymerase II promoter; response to progesterone stimulus; response to corticosterone stimulus; cellular response to hormone stimulus

Research Articles on FOS B

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Product Notes

The FOS B fosb (Catalog #AAA9402227) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOS B antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FOS B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the FOS B fosb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOS B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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