Western Blot (WB)
(Expression analysis of Formin-like protein 2. Anti-Formin-like protein 2 antibody (11-10008) was used at 4 µg/ml on HCT-116 lysate.)
Rabbit anti-Human Formin-like protein 2 Polyclonal Antibody | anti-FHOD1 antibody
Formin-like protein 2 Polyclonal Antibody
Western Blot (WB)
(Expression analysis of Formin-like protein 2. Anti-Formin-like protein 2 antibody (11-10008) was used at 4 µg/ml on HCT-116 lysate.)
Western Blot (WB)
(Expression analysis of Formin-like protein 2. Anti-Formin-like protein 2 antibody (11-10008) was used at 4 µg/ml on HCT-116 lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. [provided by RefSeq, Jul 2008]
Uniprot Description
FHOD1: a cytoskeletal protein required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Self-associates via the FH2 domain. Binds to F-actin via its N-terminus. Binds to the cytoplasmic domain of CD21 via its C- terminus.
Protein type: Actin-binding
Chromosomal Location of Human Ortholog: 16q22
Cellular Component: membrane; cytoplasm; stress fiber; nucleus
Molecular Function: identical protein binding; protein binding; actin binding
Biological Process: positive regulation of stress fiber formation; positive regulation of transcription from RNA polymerase II promoter
Research Articles on FHOD1
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Product Notes
The FHOD1 fhod1 (Catalog #AAA668132) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Formin-like protein 2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Formin-like protein 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 2-4 µg/ml. Researchers should empirically determine the suitability of the FHOD1 fhod1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Formin-like protein 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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