Rabbit CCNO Polyclonal Antibody | anti-CCNO antibody

CCNO, NT (CCNO, Cyclin-O)

Cat. Num. AAA649806

• Gene Names: CCNO; CCNU; UDG2
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: CCNO; Polyclonal Antibody; NT (CCNO; Cyclin-O); Anti -CCNO; anti-CCNO antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human CCNO/Cyclin O. Species Crossreactivity: Mouse, rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.02% sodium azide.

• Applicable Applications for anti-CCNO antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Western Blot and Immunohistochemistry.; Dilution: Western Blot: 0.5-2ug/ml; Immunohistochemistry (Paraffin): 5ug/ml
• Immunogen: Synthetic peptide corresponding to 14aa from human CCNO/Cyclin O at N-Terminal.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(CCNO/Cyclin O antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced retrieval)

Western Blot (WB)

(Western blot analysis of Cyclin O in mouse bladder tissue lysate with MBS649806 at (A) 1 and (B) 2 ug/ml.)

Related Product Information for anti-CCNO antibody

CCNO belongs to the cyclin family. Maximum levels during G1 phase. Levels decrease through S and G2 phases.

Product Categories/Family for anti-CCNO antibody

Antibodies; Abs to Cyclin

NCBI and Uniprot Product Information

• NCBI GI #: 153791755
• NCBI GeneID: 10309
• NCBI Accession #: NP_066970.3
• NCBI GenBank Nucleotide #: NM_021147.3
• UniProt Accession #: P22674; Q0P6J2; Q9H6B0; Q9UMD5; A8K1W5
• Molecular Weight: 38,096 Da
• NCBI Official Full Name: cyclin-O
• NCBI Official Synonym Full Names: cyclin O
• NCBI Official Symbol: CCNO
• NCBI Official Synonym Symbols: CCNU; UDG2
• NCBI Protein Information: cyclin-O; cyclin U; cyclin domain containing
• UniProt Protein Name: Cyclin-O
• Protein Family: Cyclin
• UniProt Gene Name: CCNO
• UniProt Entry Name: CCNO_HUMAN

NCBI Description

This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 term is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes.[provided by RefSeq, Nov 2010]

Uniprot Description

Developmental stage: Maximum levels during G1 phase. Levels decrease through S and G2 phases. Ref.6

Sequence similarities: Belongs to the cyclin family.

Caution: Was originally thought to have uracil-DNA glycosylase (UDG) activity and wrongly named UNG2 and UDG2 (Ref.1). It was later shown that it is a member of the cyclin family (Ref.6). UNG2 corresponds to the isoform 2 of UNG gene.

Sequence caution: The sequence AAB05817.1 differs from that shown. Reason: Sequencing errors.The sequence CAA36728.1 differs from that shown. Reason: Sequencing errors.