Rabbit anti-Human FN3K Polyclonal Antibody | anti-FN3K antibody

FN3K (Fructosamine-3-kinase)

Cat. Num. AAA6003548

• Reactivity: Human
• Applications: Western Blot, Immunoprecipitation
• Purity: Serum; Serum
• Synonyms: FN3K; Polyclonal Antibody; FN3K (Fructosamine-3-kinase); Anti -FN3K (Fructosamine-3-kinase); anti-FN3K antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human FN3K.
• Purity/Purification: Serum; Serum
• Form/Format: Supplied as a liquid.
• Sequence: MEQLLRAELRTATLRAFGGPGAGCISEGRAYDTDAGPVFVKVNRRTQARQMFEGEVASLEALRSTGLVRVPRPMKVIDLPGGGAAFVMEHLKMKSLSSQASKLGEQMADLHLYNQKLREKLKEEENTVGRRGEGAEPQYVDKFGFHTVTCCGFIPQVNEWQDDWPTFFARHRLQAQLDLIEKDYADREARELWSRLQVKIPDLFCGLEIVPALLHGDLWSGNVAEDDVGPIIYDPASFYGHSEFELAIALMFGGFPRSFFTAYHRKIPKAPGFDQRLLLYQLFNYLNHWNHFGREYRSPSLGTMRRLLK

• Applicable Applications for anti-FN3K antibody: Western Blot (WB), Immunoprecipitation (IP)
• Application Notes: Suitable for use in Western Blot and Immunoprecipitation.
• Immunogen: Full length human FN3K, aa1-309 (NP_071441.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of FN3K expression in transfected 293T cell line by FN3K polyclonal antibody. Lane 1: FN3K transfected lysate (35.2kD). Lane 2: Non-transfected lysate.)

Immunoprecipitation (IP)

(Immunoprecipitation of FN3K transfected lysate using FN3K rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with FN3K mouse polyclonal antibody.)

Related Product Information for anti-FN3K antibody

May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme.

Product Categories/Family for anti-FN3K antibody

Antibodies; Abs to Protein Kinases

NCBI and Uniprot Product Information

• NCBI GI #: 11545906
• NCBI GeneID: 64122
• NCBI Accession #: NP_071441.1
• NCBI GenBank Nucleotide #: NM_022158.3
• UniProt Accession #: Q9H479
• Molecular Weight: 35,171 Da
• NCBI Official Full Name: fructosamine-3-kinase
• NCBI Official Synonym Full Names: fructosamine 3 kinase
• NCBI Official Symbol: FN3K
• NCBI Protein Information: fructosamine-3-kinase
• UniProt Protein Name: Fructosamine-3-kinase
• Protein Family: Fructosamine-3-kinase
• UniProt Gene Name: FN3K
• UniProt Entry Name: FN3K_HUMAN

NCBI Description

A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]

Uniprot Description

FN3K: May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme. Belongs to the fructosamine kinase family.

Protein type: Kinase, other; EC 2.7.1.-

Chromosomal Location of Human Ortholog: 17q25.3

Molecular Function: fructosamine-3-kinase activity

Biological Process: fructoselysine metabolic process; epithelial cell differentiation; fructosamine metabolic process; phosphorylation