Western Blot (WB)
(Western Blot analysis of FMO3 expression in transfected 293T cell line by FMO3 polyclonal antibody. Lane 1: FMO3 transfected lysate (60.1kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human FMO3 Polyclonal Antibody | anti-FMO3 antibody
FMO3 (Dimethylaniline Monooxygenase [N-oxide-forming] 3, Hepatic Flavin-containing Monooxygenase 3, FMO 3, FMO Form 2, FMO II, Dimethylaniline Oxidase 3) (FITC)
Western Blot (WB)
(Western Blot analysis of FMO3 expression in transfected 293T cell line by FMO3 polyclonal antibody. Lane 1: FMO3 transfected lysate (60.1kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of FMO3 expression in transfected 293T cell line by FMO3 polyclonal antibody. Lane 1: FMO3 transfected lysate (60.1kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-,sulfur-, and phosphorous-containing xenobiotics such as therapeutic drugs, dietary compounds, pesticides, and other foreign compounds. The human FMO gene family is composed of 5 genes and multiple pseudogenes. FMO members have distinct developmental- and tissue-specific expression patterns. The expression of this FMO3 gene, the major FMO expressed in adult liver, can vary up to 20-fold between individuals. This inter-individual variation in FMO3 expression levels is likely to have significant effects on the rate at which xenobiotics are metabolised and, therefore, is of considerable interest to the pharmaceutical industry. This transmembrane protein localizes to the endoplasmic reticulum of many tissues. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Mutations in this gene cause the disorder trimethylaminuria (TMAu) which is characterized by the accumulation and excretion of unmetabolized trimethylamine and a distinctive body odor. In healthy individuals, trimethylamine is primarily converted to the non odorous trimethylamine N-oxide.[provided by RefSeq, Jan 2016]
Research Articles on FMO3
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Product Notes
The FMO3 (Catalog #AAA6378749) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FMO3 (Dimethylaniline Monooxygenase [N-oxide-forming] 3, Hepatic Flavin-containing Monooxygenase 3, FMO 3, FMO Form 2, FMO II, Dimethylaniline Oxidase 3) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FMO3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the FMO3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FMO3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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