Rabbit anti-Human FMNL3 Polyclonal Antibody | anti-FMNL3 antibody

FMNL3 Antibody

Cat. Num. AAA7043947

• Gene Names: FMNL3; FRL2; WBP3; FHOD3; WBP-3
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Immunofluorescence
• Purity: >95%, Protein G purified
• Synonyms: FMNL3; Polyclonal Antibody; FMNL3 Antibody; Formin-like protein 3; Formin homology 2 domain-containing protein 3; WW domain-binding protein 3; WBP-3; FHOD3; FRL2; KIAA2014; WBP3; anti-FMNL3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 1027

• Applicable Applications for anti-FMNL3 antibody: ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Species: Human
• Immunogen: Recombinant human Formin-like protein 3 protein
• Conjugate: Non-conjugated
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66770
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human colon cancer using MBS7043947 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7043947 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of HepG2 cells using MBS7043947 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Related Product Information for anti-FMNL3 antibody

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis (By similarity). In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignement.

NCBI and Uniprot Product Information

• NCBI GI #: 119120874
• NCBI GeneID: 91010
• NCBI Accession #: NP_783863.4
• NCBI GenBank Nucleotide #: NM_175736.4
• UniProt Accession #: Q8IVF7; Q6ZRJ1; B0JZA7
• Molecular Weight: 116,871 Da
• NCBI Official Full Name: formin-like protein 3 isoform 1
• NCBI Official Synonym Full Names: formin like 3
• NCBI Official Symbol: FMNL3
• NCBI Official Synonym Symbols: FRL2; WBP3; FHOD3; WBP-3
• NCBI Protein Information: formin-like protein 3
• UniProt Protein Name: Formin-like protein 3
• Protein Family: Formin-like protein
• UniProt Gene Name: FMNL3
• UniProt Synonym Gene Names: FHOD3; FRL2; KIAA2014; WBP3; WBP-3
• UniProt Entry Name: FMNL3_HUMAN

NCBI Description

The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

FMNL3: Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Belongs to the formin homology family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: cytoplasm; cytosol

Molecular Function: GTPase activating protein binding

Biological Process: cell migration; cytoskeleton organization and biogenesis; regulation of cell shape