Rabbit FMNL3 Polyclonal Antibody | anti-FMNL3 antibody

FMNL3 Polyclonal Antibody

Cat. Num. AAA3015327

• Gene Names: FMNL3; FRL2; WBP3; FHOD3; WBP-3
• Reactivity: Human, Mouse, Rat, Dog, Cow
• Applications: Immunohistochemistry
• Purity: affinity purified by Protein A
• Synonyms: FMNL3; Polyclonal Antibody; FMNL3 Polyclonal Antibody; FHOD3; FMNL3_HUMAN; Formin homology 2 domain containing protein 3; Formin like protein 3; WBP3; WW domain binding protein 3. ; anti-FMNL3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat, Dog, Cow
• Clonality: Polyclonal
• Specificity: FMNL3 Polyclonal Antibody detects endogenous levels of FMNL3 protein.
• Purity/Purification: affinity purified by Protein A
• Form/Format: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Applicable Applications for anti-FMNL3 antibody: Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: IHC-P: 1:100-500
• Immunogen: KLH conjugated synthetic peptide derived from human FMNL3:951-1028/1028
• Preparation and Storage: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FMNL3) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C)

Related Product Information for anti-FMNL3 antibody

The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described

NCBI and Uniprot Product Information

• NCBI GI #: 119120874
• NCBI GeneID: 91010
• NCBI Accession #: NP_783863.4
• NCBI GenBank Nucleotide #: NM_175736.4
• UniProt Accession #: Q8IVF7; Q6ZRJ1; B0JZA7
• Molecular Weight: 116,871 Da
• NCBI Official Full Name: formin-like protein 3 isoform 1
• NCBI Official Synonym Full Names: formin like 3
• NCBI Official Symbol: FMNL3
• NCBI Official Synonym Symbols: FRL2; WBP3; FHOD3; WBP-3
• NCBI Protein Information: formin-like protein 3
• UniProt Protein Name: Formin-like protein 3
• Protein Family: Formin-like protein
• UniProt Gene Name: FMNL3
• UniProt Synonym Gene Names: FHOD3; FRL2; KIAA2014; WBP3; WBP-3

NCBI Description

The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. Required for developmental angiogenesis (). In this process, required for microtubule reorganization and for efficient endothelial cell elongation. In quiescent endothelial cells, triggers rearrangement of the actin cytoskeleton, but does not alter microtubule alignement.