Rabbit FLJ20097 Polyclonal Antibody | anti-VPS50 antibody
FLJ20097 Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
FLJ20097; Polyclonal Antibody; FLJ20097 Antibody; CC132_HUMAN; CCDC 132; CCDC132; Coiled coil domain containing 132; Coiled coil domain containing protein 132; Coiled-coil domain-containing protein 132; EARP/GARPII complex subunit VPS50; FLJ23581; KIAA1861; MGC176659; Syndetin; VPS50; VPS50 EARP/GARPII complex subunit; VPS54L; anti-VPS50 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
FLJ20097 Antibody detects endogenous levels of total FLJ20097.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-VPS50 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the syndetin family.
Subunit Structure
Component of the endosome-associated retrograde protein (EARP) complex, composed of VPS51, VPS52, VPS53 and VPS50/Syndetin. The EARP complex interacts with EIPR1.
Tissue Specificity
Ubiquitous, with higher expression in brain and skeletal muscle.
Function
Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-VPS50 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
111,174 Da
NCBI Official Full Name
coiled-coil domain-containing protein 132 isoform c
NCBI Official Synonym Full Names
coiled-coil domain containing 132
NCBI Official Symbol
CCDC132
NCBI Protein Information
coiled-coil domain-containing protein 132
UniProt Protein Name
Coiled-coil domain-containing protein 132
Protein Family
UniProt Gene Name
CCDC132
UniProt Synonym Gene Names
KIAA1861
UniProt Entry Name
CC132_HUMAN
Uniprot Description
Tissue specificity: Ubiquitous, with higher expression in brain and skeletal muscle. Ref.3
Sequence caution: The sequence BAB15701.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB47490.2 differs from that shown. Reason: Frameshift at position 2.
Research Articles on VPS50
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Product Notes
The VPS50 ccdc132 (Catalog #AAA9629168) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FLJ20097 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FLJ20097 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the VPS50 ccdc132 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLJ20097, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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