Immunohistochemistry (IHC)
(Anti-GPR81 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit FKSG80 / GPR81 Polyclonal Antibody | anti-FKSG80 antibody
Rabbit Polyclonal to Human FKSG80 / GPR81
Gene Names
HCAR1; HCA1; GPR81; LACR1; FKSG80; GPR104; TAGPCR; TA-GPCR
Reactivity
Human, MonkeyPredicted Reactivity: Gorilla (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, ELISA
Purity
Immunoaffinity Purified
Synonyms
FKSG80 / GPR81; Polyclonal Antibody; Rabbit Polyclonal to Human FKSG80 / GPR81; Anti-FKSG80 / GPR81 Antibody (N-Terminus) IHC-plus; HCAR1; FKSG80; G protein-coupled receptor 81; G-protein coupled receptor 104; G protein-coupled receptor 104; G-protein coupled receptor 81; GPR81; GPR104; LACR1; HCA1; TA-GPCR; Lactate receptor 1; Human FKSG80; anti-FKSG80 antibody
Host
Rabbit
Reactivity
Human, Monkey
Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity)
Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human GPR81. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
346
Applicable Applications for anti-FKSG80 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA, IHC-P (20 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPR81. Percent identity with other species by BLAST analysis: Human, Monkey (100%); Gorilla (95%); Marmoset (89%); Dog, Hamster, Elephant (84%).
Immunogen Type
Synthetic peptide
Immunogen
FKSG80 / GPR81 antibody was raised against synthetic 19 amino acid peptide from N-terminal extracellular domain of human GPR81. Percent identity with other species by BLAST analysis: Human, Monkey (100%); Gorilla (95%); Marmoset (89%); Dog, Hamster, Elephant (84%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Immunohistochemistry (IHC)
(Anti-GPR81 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GPR81 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-FKSG80 antibody
The receptor FKSG80/GPR81 is a member of the Chemokine Receptor subfamily.
Product Categories/Family for anti-FKSG80 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,295 Da
NCBI Official Full Name
hydroxycarboxylic acid receptor 1
NCBI Official Synonym Full Names
hydroxycarboxylic acid receptor 1
NCBI Official Symbol
HCAR1
NCBI Official Synonym Symbols
HCA1; GPR81; LACR1; FKSG80; GPR104; TAGPCR; TA-GPCR
NCBI Protein Information
hydroxycarboxylic acid receptor 1; lactate receptor 1; G protein-coupled receptor 81; G-protein coupled receptor 81; G protein-coupled receptor 104; G-protein coupled receptor 104; hydroxy-carboxylic acid receptor 1; T-cell activation G protein-coupled receptor
UniProt Protein Name
Hydroxycarboxylic acid receptor 1
UniProt Gene Name
HCAR1
UniProt Synonym Gene Names
GPR104; GPR81; HCA1
UniProt Entry Name
HCAR1_HUMAN
NCBI Description
G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM, Feb 2005]
Uniprot Description
Gpr81: Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; response to estradiol stimulus
Research Articles on FKSG80
Similar Products
Product Notes
The FKSG80 hcar1 (Catalog #AAA240915) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human FKSG80 / GPR81 reacts with Human, Monkey Predicted Reactivity: Gorilla (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's FKSG80 / GPR81 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA, IHC-P (20 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the FKSG80 hcar1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FKSG80 / GPR81, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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