Rabbit anti-Rat Fibroblast Growth Factor 13 (FGF13) Polyclonal Antibody | anti-FGF13 antibody
Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13)
MGHHHHHHSG SEF- MALLRKSYSE PQLKGIVTKL YSRQGYHLQL QADGTIDGTK DEDSTYTLFN LIPVGLRVVA IQGVQTKLYL AMNSEGYLYT SEHFTPECKF KESVFENYYV TYSSMIYRQQ QSGRGWYLGL NKEGEIMKGN HVKKNKPAAH FLPKPLKVAM YKEPSLHDLT EFSRSGSGTP TKSRSVSGVL NGGKSMSHNE ST
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
NCBI and Uniprot Product Information
NCBI Description
may play a role in differentiation of cortical neurons [RGD, Feb 2006]
Uniprot Description
FGF13: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Belongs to the heparin-binding growth factors family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell development/differentiation; Nucleolus
Chromosomal Location of Human Ortholog: Xq36
Cellular Component: axon; cytoplasm; cytosol; dendrite; extracellular region; filopodium; growth cone; lateral plasma membrane; microtubule; neuron projection; nucleus; plasma membrane
Molecular Function: beta-tubulin binding; growth factor activity; microtubule binding; protein kinase activator activity; sodium channel regulator activity
Biological Process: activation of protein kinase activity; apoptosis; cell proliferation; cerebral cortex cell migration; establishment of neuroblast polarity; hippocampus development; learning; MAPK cascade; memory; microtubule polymerization; negative regulation of collateral sprouting; negative regulation of microtubule depolymerization; neuron migration; sodium ion transport
Research Articles on FGF13
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Product Notes
The FGF13 fgf13 (Catalog #AAA2002744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Fibroblast Growth Factor 13 (FGF13) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the FGF13 fgf13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- MALLRKSYSE PQLKGIVTKL YSRQGYHLQL QADGTIDGTK DEDSTYTLFN LIPVGLRVVA IQGVQTKLYL AMNSEGYLYT SEHFTPECKF KESVFENYYV TYSSMIYRQQ QSGRGWYLGL NKEGEIMKGN HVKKNKPAAH FLPKPLKVAM YKEPSLHDLT EFSRSGSGTP TKSRSVSGVL NGGKSMSHNE ST. It is sometimes possible for the material contained within the vial of "Fibroblast Growth Factor 13 (FGF13), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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