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Western Blot (WB) (Western Blot: Sample: Recombinant protein.)

Rabbit anti-Rat Fibroblast Growth Factor 13 (FGF13) Polyclonal Antibody | anti-FGF13 antibody

Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13)

Gene Names
Fgf13; FGF-13
Reactivity
Rat
Applications
Immunocytochemistry, Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Chromatography
Synonyms
Fibroblast Growth Factor 13 (FGF13); Polyclonal Antibody; Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13); anti-FGF13 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Rat
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against FGF13. It has been selected for its ability to recognize FGF13 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF- MALLRKSYSE PQLKGIVTKL YSRQGYHLQL QADGTIDGTK DEDSTYTLFN LIPVGLRVVA IQGVQTKLYL AMNSEGYLYT SEHFTPECKF KESVFENYYV TYSSMIYRQQ QSGRGWYLGL NKEGEIMKGN HVKKNKPAAH FLPKPLKVAM YKEPSLHDLT EFSRSGSGTP TKSRSVSGVL NGGKSMSHNE ST
Sequence Length
245
Applicable Applications for anti-FGF13 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunogen
Recombinant FGF13 (Met1~Thr192) expressed in E.coli.
Cross Reactivity
Rat
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2068957
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant protein.)

Western Blot (WB) (Western Blot: Sample: Recombinant protein.)

Immunohistochemistry (IHC)

(DAB staining on fromalin fixed paraffin- embedded liver tissue))

Immunohistochemistry (IHC) (DAB staining on fromalin fixed paraffin- embedded liver tissue))

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Rat Spleen Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Rat Spleen Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,605 Da
NCBI Official Full Name
fibroblast growth factor 13
NCBI Official Synonym Full Names
fibroblast growth factor 13
NCBI Official Symbol
Fgf13
NCBI Official Synonym Symbols
FGF-13
NCBI Protein Information
fibroblast growth factor 13
UniProt Protein Name
Fibroblast growth factor 13
Protein Family
UniProt Gene Name
Fgf13
UniProt Synonym Gene Names
FGF-13

NCBI Description

may play a role in differentiation of cortical neurons [RGD, Feb 2006]

Uniprot Description

FGF13: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Belongs to the heparin-binding growth factors family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Nucleolus

Chromosomal Location of Human Ortholog: Xq36

Cellular Component: axon; cytoplasm; cytosol; dendrite; extracellular region; filopodium; growth cone; lateral plasma membrane; microtubule; neuron projection; nucleus; plasma membrane

Molecular Function: beta-tubulin binding; growth factor activity; microtubule binding; protein kinase activator activity; sodium channel regulator activity

Biological Process: activation of protein kinase activity; apoptosis; cell proliferation; cerebral cortex cell migration; establishment of neuroblast polarity; hippocampus development; learning; MAPK cascade; memory; microtubule polymerization; negative regulation of collateral sprouting; negative regulation of microtubule depolymerization; neuron migration; sodium ion transport

Research Articles on FGF13

Similar Products

Product Notes

The FGF13 fgf13 (Catalog #AAA2002744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Fibroblast Growth Factor 13 (FGF13) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Fibroblast Growth Factor 13 (FGF13) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the FGF13 fgf13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- MALLRKSYSE PQLKGIVTKL YSRQGYHLQL QADGTIDGTK DEDSTYTLFN LIPVGLRVVA IQGVQTKLYL AMNSEGYLYT SEHFTPECKF KESVFENYYV TYSSMIYRQQ QSGRGWYLGL NKEGEIMKGN HVKKNKPAAH FLPKPLKVAM YKEPSLHDLT EFSRSGSGTP TKSRSVSGVL NGGKSMSHNE ST. It is sometimes possible for the material contained within the vial of "Fibroblast Growth Factor 13 (FGF13), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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