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Chemiluminescence ((0.1ug/ml) MBS628273 staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Goat anti-Human Fibrinogen-like Protein 1 Polyclonal Antibody | anti-FGL1 antibody

Fibrinogen-like Protein 1 (FGL1, Hepassocin, Fibrinogen-like 1)

Gene Names
FGL1; HFREP1; HP-041; LFIRE1; MGC12455
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by peptide affinity chromatography.
Synonyms
Fibrinogen-like Protein 1; Polyclonal Antibody; Fibrinogen-like Protein 1 (FGL1; Hepassocin; Fibrinogen-like 1); Anti -Fibrinogen-like Protein 1 (FGL1; anti-FGL1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human FGL1. Species sequence homology: mouse, rat, canine, bovine.
Purity/Purification
Affinity Purified
Purified by peptide affinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
Applicable Applications for anti-FGL1 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: Peptide ELISA Titer: 1:16,000
Western Blot: 0.1-0.3ug/ml detects an~ 35kD band observed in Human Liver lysates (calculated MW of 36.4kD according to NP_004458.3).
Immunogen
Synthetic peptide corresponding to C-ETRVKQQQVKIKQ, from the internal region of human FGL1 (NP_004458.3).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chemiluminescence

((0.1ug/ml) MBS628273 staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Chemiluminescence ((0.1ug/ml) MBS628273 staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-FGL1 antibody
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
Product Categories/Family for anti-FGL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,379 Da
NCBI Official Full Name
fibrinogen-like protein 1
NCBI Official Synonym Full Names
fibrinogen-like 1
NCBI Official Symbol
FGL1
NCBI Official Synonym Symbols
HFREP1; HP-041; LFIRE1; MGC12455
NCBI Protein Information
fibrinogen-like protein 1; LFIRE-1; hepassocin; OTTHUMP00000122468; OTTHUMP00000224774; OTTHUMP00000224775; OTTHUMP00000224776; OTTHUMP00000224916; liver fibrinogen-related protein 1; hepatocellular carcinoma-related sequence; hepatocyte-derived fibrinogen-related protein 1
UniProt Protein Name
Fibrinogen-like protein 1
Protein Family
UniProt Gene Name
FGL1
UniProt Synonym Gene Names
HFREP1
UniProt Entry Name
FGL1_HUMAN

NCBI Description

Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq]

Uniprot Description

FGL1: Has hepatocyte mitogenic activity.

Protein type: Secreted; Secreted, signal peptide; Extracellular matrix

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: fibrinogen complex

Biological Process: cholesterol metabolic process

Research Articles on FGL1

Similar Products

Product Notes

The FGL1 fgl1 (Catalog #AAA628273) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Fibrinogen-like Protein 1 (FGL1, Hepassocin, Fibrinogen-like 1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Fibrinogen-like Protein 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: Peptide ELISA Titer: 1:16,000 Western Blot: 0.1-0.3ug/ml detects an~ 35kD band observed in Human Liver lysates (calculated MW of 36.4kD according to NP_004458.3). Researchers should empirically determine the suitability of the FGL1 fgl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Fibrinogen-like Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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