Western Blot (WB)
(FBXL8 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FBXL8 antibody detected the FBXL8 protein (arrow).)
Rabbit anti-Human FBXL8 Polyclonal Antibody | anti-FBXL8 antibody
FBXL8 Antibody (N-term)
Gene Names
FBXL8; FBL8
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
FBXL8; Polyclonal Antibody; FBXL8 Antibody (N-term); F-box/LRR-repeat protein 8; F-box and leucine-rich repeat protein 8; F-box protein FBL8; FBL8; anti-FBXL8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This FBXL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-83 amino acids from the N-terminal region of human FBXL8.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.47 (varies by lot)
Sequence Positions
57-83
Sequence Length
374
Applicable Applications for anti-FBXL8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(FBXL8 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FBXL8 antibody detected the FBXL8 protein (arrow).)
Western Blot (WB)
(FBXL8 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FBXL8 antibody detected the FBXL8 protein (arrow).)
Related Product Information for anti-FBXL8 antibody
This gene encodes a member of the F-box protein family
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into 3 classes: Fbws
containing WD-40 domains, Fbls containing leucine-rich repeats, and
Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene
belongs to the Fbls class. It shares 78% sequence identity with the
mouse protein.
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into 3 classes: Fbws
containing WD-40 domains, Fbls containing leucine-rich repeats, and
Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene
belongs to the Fbls class. It shares 78% sequence identity with the
mouse protein.
Product Categories/Family for anti-FBXL8 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lievens, S., et al. J. Proteome Res. 8(2):877-886(2009)
Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lievens, S., et al. J. Proteome Res. 8(2):877-886(2009)
Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40516
NCBI Official Full Name
F-box/LRR-repeat protein 8
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 8
NCBI Official Symbol
FBXL8
NCBI Official Synonym Symbols
FBL8
NCBI Protein Information
F-box/LRR-repeat protein 8
UniProt Protein Name
F-box/LRR-repeat protein 8
Protein Family
UniProt Gene Name
FBXL8
UniProt Synonym Gene Names
FBL8
UniProt Entry Name
FBXL8_HUMAN
NCBI Description
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008]
Uniprot Description
FBXL8: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.
Chromosomal Location of Human Ortholog: 16q22.1
Molecular Function: protein binding
Research Articles on FBXL8
Similar Products
Product Notes
The FBXL8 fbxl8 (Catalog #AAA9213411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 57-83. The FBXL8 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FBXL8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the FBXL8 fbxl8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXL8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
