Rabbit anti-Human FBXL8 Polyclonal Antibody | anti-FBXL8 antibody

FBXL8, NT (FBXL8, FBL8, F-box/LRR-repeat protein 8, F-box and leucine-rich repeat protein 8, F-box protein FBL8) (Biotin)

Cat. Num. AAA6298298

• Gene Names: FBXL8; FBL8
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: FBXL8; Polyclonal Antibody; NT (FBXL8; FBL8; F-box/LRR-repeat protein 8; F-box and leucine-rich repeat protein 8; F-box protein FBL8) (Biotin); F-box protein FBL8; anti-FBXL8 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-FBXL8 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: FBXL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human FBXL8.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(FBXL8 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FBXL8 antibody detected the FBXL8 protein (arrow).)

Product Categories/Family for anti-FBXL8 antibody

Antibodies; Ubiquitin Ligases

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). Lievens, S., et al. J. Proteome Res. 8(2):877-886(2009). Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999).

NCBI and Uniprot Product Information

• NCBI GI #: 22547146
• NCBI GeneID: 55336
• NCBI Accession #: NP_060848.2
• NCBI GenBank Nucleotide #: NM_018378.2
• UniProt Accession #: Q96CD0; Q9NUM0
• Molecular Weight: 40,516 Da
• NCBI Official Full Name: F-box/LRR-repeat protein 8
• NCBI Official Synonym Full Names: F-box and leucine rich repeat protein 8
• NCBI Official Symbol: FBXL8
• NCBI Official Synonym Symbols: FBL8
• NCBI Protein Information: F-box/LRR-repeat protein 8
• UniProt Protein Name: F-box/LRR-repeat protein 8
• Protein Family: F-box/LRR-repeat protein
• UniProt Gene Name: FBXL8
• UniProt Synonym Gene Names: FBL8
• UniProt Entry Name: FBXL8_HUMAN

NCBI Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008]