Rabbit anti-Human, Mouse FBXL4 Polyclonal Antibody | anti-FBXL4 antibody

FBXL4 Antibody

Cat. Num. AAA9430529

• Gene Names: FBXL4; FBL4; FBL5; MTDPS13
• Reactivity: Human, Mouse
• Applications: Western Blot, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: FBXL4; Polyclonal Antibody; FBXL4 Antibody; FBL4; FBL5; MTDPS13; anti-FBXL4 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total FBXL4 protein.
• Purity/Purification: Antigen affinity purification
• Form/Format: pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: 0.7 mg/mL (varies by lot)
• Sequence Length: 621

• Applicable Applications for anti-FBXL4 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:200-1000; IHC: 1:30-150
• Immunogen: Synthetic peptide of human FBXL4
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C.

SDS-Page

(Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: LOVO cell lysate, Primary antibody:47547(FBXL4 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 47547(FBXL4 Antibody) at dilution 1/25.(Original magnification: 200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 47547(FBXL4 Antibody) at dilution 1/25.(Original magnification: 200))

Related Product Information for anti-FBXL4 antibody

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.

Product Categories/Family for anti-FBXL4 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 524585204
• NCBI GeneID: 26235
• NCBI Accession #: NP_001265645.1
• NCBI GenBank Nucleotide #: NM_001278716.2
• UniProt Accession #: Q9UKA2; O95919; Q5BJH0; Q9UJU0; B2R7Q5; E1P530
• Molecular Weight: 70 kDa
• NCBI Official Full Name: F-box/LRR-repeat protein 4
• NCBI Official Synonym Full Names: F-box and leucine rich repeat protein 4
• NCBI Official Symbol: FBXL4
• NCBI Official Synonym Symbols: FBL4; FBL5; MTDPS13
• NCBI Protein Information: F-box/LRR-repeat protein 4
• UniProt Protein Name: F-box/LRR-repeat protein 4
• UniProt Gene Name: FBXL4
• UniProt Synonym Gene Names: FBL4; FBL5

NCBI Description

This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]