Rabbit anti-Mouse FBX41 Polyclonal Antibody | anti-FBX41 antibody

FBX41, NT (FBXO41, FBX41, KIAA1940, F-box only protein 41) (Biotin)

Cat. Num. AAA6298199

• Gene Names: FBXO41; FBX41
• Reactivity: Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: FBX41; Polyclonal Antibody; NT (FBXO41; KIAA1940; F-box only protein 41) (Biotin); FBXO41; F-box only protein 41; anti-FBX41 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-FBX41 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: FBX41 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the N-terminal region of human FBX41.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(FBX41 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the FBX41 antibody detected the FBX41 protein (arrow).)

Related Product Information for anti-FBX41 antibody

Members of the F-box protein family, such as FBXO41, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Product Categories/Family for anti-FBX41 antibody

Antibodies; Ubiquitin Ligases

References

Jin, J., et al. Genes Dev. 18(21):2573-2580(2004). Watanabe, N., et al. Proc. Natl. Acad. Sci. U.S.A. 101(13):4419-4424(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 289803020
• NCBI GeneID: 150726
• NCBI Accession #: NP_001073879.2
• NCBI GenBank Nucleotide #: NM_001080410.2
• UniProt Accession #: Q8TF61; Q2M1V8; G3V0Z7
• Molecular Weight: 94,496 Da
• NCBI Official Full Name: F-box only protein 41
• NCBI Official Synonym Full Names: F-box protein 41
• NCBI Official Symbol: FBXO41
• NCBI Official Synonym Symbols: FBX41
• NCBI Protein Information: F-box only protein 41
• UniProt Protein Name: F-box only protein 41
• UniProt Gene Name: FBXO41
• UniProt Synonym Gene Names: FBX41; KIAA1940
• UniProt Entry Name: FBX41_HUMAN

NCBI Description

This gene encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the SCF ubiquitin protein ligase complex that plays a role in phosphorylation-dependent ubiquitination. F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains, FBXL proteins contain leucine-rich repeats, and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the FBXO class. [provided by RefSeq, Feb 2014]