Rabbit anti-Human Fatty Acid Binding Protein, Heart, Adipocyte Polyclonal Antibody | anti-Fabp3 antibody

Fatty Acid Binding Protein, Heart, Adipocyte (FABP)

Cat. Num. AAA614864

• Gene Names: Fabp3; Fabp3
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Serum; Serum
• Synonyms: Fatty Acid Binding Protein; Heart; Adipocyte; Polyclonal Antibody; Adipocyte (FABP); Anti -Fatty Acid Binding Protein; anti-Fabp3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes Fatty Acid Binding Protein (FABP), Heart, Adipocyte. Isoform Sequence Homology
• Purity/Purification: Serum; Serum
• Form/Format: Supplied as a liquid in 0.1% sodium azide, 40% glycerol.

• Applicable Applications for anti-Fabp3 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: Western Blot: 1:1000-1:5000.; ELISA: 1:1,000-1:10,000. Coat with 5-10ug F0019-77E.
• Immunogen: 12aa synthetic peptide corresponding to the C-terminus of human FABP (KLH).
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-Fabp3 antibody

Fatty acids are important for general cellular metabolism. A number of proteins have been implicated in the transport and storage of fatty acid. FABPs (fatty acid binding proteins) are a group of cytoplasmic, small mol wt (14-15kD). FABP's have a widespread tissue distribution. FABPs are quite abundant (3-5% of total cellular protein). At least 7 FABPs, FABP1-7, have been cloned and characterized from various tissues. FABPs can bind long-chain fatty acid, fatty-acid acyl-CoA and acyl-L-carnitine. Several different isoforms of FABP have been identified. These isoforms are generally referred to by tissue type (liver, heart, intestine, adipocyte, kidney, brain, etc. For example, protein designated as H-FABP indicates that it is heart type). Expression of these isoforms is not exclusive. More than one isoform can be found in a given cell or tissue. Three main types of FABPs that were initially discovered in the heart (FABP-H), liver (FABP-L), and intestine (FABP-I) are not exclusive to these tissues and show considerable differences at the amino acid level (~30% identity). Other FABPs detected in adipocyte, kidney, and brain show a high degree of sequence homology among each other and with other FABPs.

Product Categories/Family for anti-Fabp3 antibody

Antibodies; Abs to Fatty Acid Binding Protein

NCBI and Uniprot Product Information

• NCBI GI #: 13162363
• NCBI GeneID: 79131
• NCBI Accession #: NP_077076.1
• NCBI GenBank Nucleotide #: NM_024162.1
• UniProt Accession #: P07483; Q9QY04
• Molecular Weight: 14,775 Da
• NCBI Official Full Name: fatty acid-binding protein, heart
• NCBI Official Synonym Full Names: fatty acid binding protein 3, muscle and heart
• NCBI Official Symbol: Fabp3
• NCBI Official Synonym Symbols: Fabp3
• NCBI Protein Information: fatty acid-binding protein, heart; H-FABP; fatty acid-binding protein 3; heart fatty acid binding protein; Fatty acid binding protein 3 heart; fatty acid binding protein 3 heart; heart-type fatty acid-binding protein
• UniProt Protein Name: Fatty acid-binding protein, heart
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: Fabp3
• UniProt Entry Name: FABPH_RAT

NCBI Description

binds fatty acids; may play a role in fatty acid metabolism possibly including mitochondrial beta-oxidation of fatty acids [RGD]

Uniprot Description

FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Cellular Component: extracellular space; mitochondrion; sarcoplasmic reticulum; cytoplasm; cytosol; sarcoplasm

Molecular Function: icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity; fatty acid binding

Biological Process: response to drug; long-chain fatty acid transport; cholesterol homeostasis; fatty acid beta-oxidation; regulation of fatty acid oxidation; fatty acid metabolic process; phospholipid homeostasis; response to insulin stimulus