Chicken FAK1 Polyclonal Antibody | anti-FAK1 antibody

FAK1 Antibody FITC-Conjugated

Cat. Num. AAA541570

• Gene Names: PTK2; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Synonyms: FAK1; Polyclonal Antibody; FAK1 Antibody FITC-Conjugated; FADK 1; FADK; FAK 1; FAK related non kinase polypeptide; Focal adhesion kinase 1; Focal adhesion Kinase; Focal adhesion kinase isoform FAK Del33; Focal adhesion kinase related nonkinase; FRNK; p125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; Protein tyrosine kinase 2; Protein Tyrosine Kinase Cytoplasmic; Protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2 antibody; anti-FAK1 antibody

• Host: Chicken
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Form/Format: FITC-Conjugated
• Concentration: 0.6 ug/ul in antibody stabilization buffer (varies by lot)
• Sequence Length: 1074

• Applicable Applications for anti-FAK1 antibody: ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
• Application Notes: Confocal Microscopy||1:100; Dot Blot: 1:10,000; ELISA: 1:10,000; Immunocytochemistry: 1:100; Immunofluorescence: 1:100; Immunohistochemistry: 1:100; Immunoprecipitation: 1:200; Western Blot: 1:500
• Immunogen: Synthetic peptide taken within amino acid region 740-790 on human focal adhesion kinase 1 protein.
• Immunoglobulin: IgY
• Expression: Detected in B and T-lymphocytes. Isoform 1 and isoform 6 are detected in lung fibroblasts (at protein level). Ubiquitous.
• Molecular Function: Developmental protein; Kinase; Transferase; Tyrosine-protein kinase
• Structure: Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily.; Contains 1 FERM domain.; Contains 1 protein kinase domain.
• Subcellular Location: Cell junction degree focal adhesion; Cell membrane; Peripheral membrane protein; Cytoplasmic side; Cytoplasm degree cell cortex; Cytoplasm degree cytoskeleton; Cytoplasm degree cytoskeleton degree microtubule organizing center degree centrosome; Nucleus
• Preparation and Storage: -20 degree C for long term storage

Related Product Information for anti-FAK1 antibody

FITC-Conjugated Focal Adhesion Kinase 1 Antibody
Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell

NCBI and Uniprot Product Information

• NCBI GI #: 27886593
• NCBI GeneID: 5747
• NCBI Accession #: NP_005598.3
• NCBI GenBank Nucleotide #: NM_005607.4
• UniProt Accession #: Q59GM6; Q05397
• Molecular Weight: 114,157 Da
• NCBI Official Full Name: focal adhesion kinase 1 isoform b
• NCBI Official Synonym Full Names: protein tyrosine kinase 2
• NCBI Official Symbol: PTK2
• NCBI Official Synonym Symbols: FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
• NCBI Protein Information: focal adhesion kinase 1
• UniProt Protein Name: PTK2 protein tyrosine kinase 2 isoform b variant
• UniProt Entry Name: Q59GM6_HUMAN

NCBI Description

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015]