Rabbit anti-Human FADS3 Polyclonal Antibody | anti-FADS3 antibody

FADS3 (Fatty Acid Desaturase 3, Cytochrome b5-related Protein, CYB5RP)

Cat. Num. AAA647148

• Gene Names: FADS3; CYB5RP; LLCDL3
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: FADS3; Polyclonal Antibody; FADS3 (Fatty Acid Desaturase 3; Cytochrome b5-related Protein; CYB5RP); Anti -FADS3 (Fatty Acid Desaturase 3; anti-FADS3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human FADS3.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MGGVGEPGPREGPAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAEDATDAFRAFHQDLNFVRKFLQPLLIGELAPEEPSQDGPLNAQLVEDFRALHQAAEDMKLFDASPTFFAFLLGHILAMEVLAWLLIYLLGPGWVPSALAAFILAISQAQSWCLQHDLGHASIFKKSWWNHVAQKFVMGQLKGFSAHWWNFRHFQHHAKPNIFHKDPDVTVAPVFLLGESSVEYGKKKRRYLPYNQQHLYFFLIGPPLLTLVNFEVENLAYMLVCMQWADLLWAASFYARFFLSYLPFYGVPGVLLFFVAVRVLESHWFVWITQMNHIPKEIGHEKHRDWVSSQLAATCNVEPSLFTNWFSGHLNFQIEHHLFPRMPRHNYSRVAPLVKSLCAKHGLSYEVKPFLTALVDIVRSLKKSGDIWLDAYLHQ

• Applicable Applications for anti-FADS3 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human FADS3, aa1-445 (NP_068373.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of FADS3 expression in transfected 293T cell line by FADS3 polyclonal antibody. Lane 1: FADS3 transfected lysate (51.1kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-FADS3 antibody

Antibodies; Abs to Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 13375616
• NCBI GeneID: 3995
• NCBI Accession #: NP_068373.1
• NCBI GenBank Nucleotide #: NM_021727.4
• UniProt Accession #: Q9Y5Q0; O60426
• Molecular Weight: 51,145 Da
• NCBI Official Full Name: fatty acid desaturase 3
• NCBI Official Synonym Full Names: fatty acid desaturase 3
• NCBI Official Symbol: FADS3
• NCBI Official Synonym Symbols: CYB5RP; LLCDL3
• NCBI Protein Information: fatty acid desaturase 3; delta-9-desaturase; cytochrome b5-related protein; delta-9 fatty acid desaturase; linoleoyl-CoA desaturase (delta-9-desaturase)-like 3
• UniProt Protein Name: Fatty acid desaturase 3
• Protein Family: Fatty acid desaturase
• UniProt Gene Name: FADS3
• UniProt Synonym Gene Names: CYB5RP
• UniProt Entry Name: FADS3_HUMAN

NCBI Description

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008]

Uniprot Description

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

By similarity.

Tissue specificity: Has been found in heart, liver, lung, uterus, and brainstem. Ref.1

Domain: The histidine box domains may contain the active site and/or be involved in metal ion binding.

Sequence similarities: Belongs to the fatty acid desaturase family.Contains 1 cytochrome b5 heme-binding domain.

Sequence caution: The sequence AAC23396.1 differs from that shown. Reason: Erroneous gene model prediction.