Rabbit anti-Human FABP3 Polyclonal Antibody | anti-FABP3 antibody

FABP3 Antibody

Cat. Num. AAA840231

• Gene Names: FABP1; FABPL; L-FABP
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity purified
• Synonyms: FABP3; Polyclonal Antibody; FABP3 Antibody; FABP; FABP-3; FABP 3; Fatty acid-binding protein; mammary-derived growth inhibitor; anti-FABP3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purified
• Form/Format: 100 ug (0.5 mg/ml) affinity purified rabbit anti-human FABP3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.55 BSA and 0.01% thimerosal.; Appearance: Colorless liquid
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 127

• Applicable Applications for anti-FABP3 antibody: Western Blot (WB)
• Application Notes: Western blot analysis (0.5-4 ug/ml). Per researchers feedback, it can also be used in neutralization (3-6 ug/ml). However, the optimal conditions should be determined individually.
• Immunogen: E. coli expressed human FABP3
• Handling: The antibody solution should be gently mixed before use.
• Preparation and Storage: At -20 degree C; Shelf Life: 12 months

Testing Data

Related Product Information for anti-FABP3 antibody

Background: Human Fatty Acid Binding Protein-3 (FABP-3) exhibits high affinity for small lipophilic ligands. Studies smuggest that FABPs are involved in the uptake and metabolism of fatty acids, maintenance of cellular membrane fatty acids levels, intracellular trafficking, modulation of specific enzymes of lipid metabolic pathways, as well as in the modulation of cell growth and differentiation.

NCBI and Uniprot Product Information

• NCBI GI #: 4557577
• NCBI GeneID: 2168
• NCBI Accession #: NP_001434
• NCBI GenBank Nucleotide #: NM_001443.2
• Molecular Weight: 14,208 Da
• NCBI Official Full Name: fatty acid-binding protein, liver
• NCBI Official Synonym Full Names: fatty acid binding protein 1, liver
• NCBI Official Symbol: FABP1
• NCBI Official Synonym Symbols: FABPL; L-FABP
• NCBI Protein Information: fatty acid-binding protein, liver
• UniProt Protein Name: Fatty acid-binding protein, liver
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP1
• UniProt Synonym Gene Names: FABPL; L-FABP
• UniProt Entry Name: FABPL_HUMAN

NCBI Description

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

Uniprot Description

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p11

Cellular Component: nucleoplasm; peroxisomal matrix; apical cortex; cytosol

Molecular Function: antioxidant activity; bile acid binding; phospholipid binding; chromatin binding; drug binding; long-chain fatty acid transporter activity; fatty acid binding

Biological Process: long-chain fatty acid transport; positive regulation of hydrolase activity; positive regulation of cell proliferation; negative regulation of caspase activity; cellular lipid metabolic process; positive regulation of fatty acid beta-oxidation; negative regulation of apoptosis; intestinal absorption