Western Blot (WB)
(WB Suggested Anti-C17orf70 AntibodyTitration: 1.0 ug/mlPositive Control: Placenta)
Rabbit anti-Human FAAP100 Polyclonal Antibody | anti-FAAP100 antibody
FAAP100 Antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-C17orf70 AntibodyTitration: 1.0 ug/mlPositive Control: Placenta)
Western Blot (WB)
(WB Suggested Anti-C17orf70 AntibodyTitration: 1.0 ug/mlPositive Control: Placenta)
Target Description: FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 (see MIM 227646) monoubiquitination (Ling et al., 2007 [PubMed 17396147]).[supplied by OMIM, Mar 2008]
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]
Uniprot Description
GMPR: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family.
Protein type: Nucleotide Metabolism - purine; Oxidoreductase; EC 1.7.1.7
Chromosomal Location of Human Ortholog: 6p23
Cellular Component: cytosol
Molecular Function: GMP reductase activity; metal ion binding
Biological Process: nucleobase, nucleoside and nucleotide metabolic process; nucleotide metabolic process; response to cold; purine base metabolic process; purine salvage
Research Articles on FAAP100
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Product Notes
The FAAP100 gmpr (Catalog #AAA3215665) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FAAP100 Antibody - N-terminal region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FAAP100 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the FAAP100 gmpr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: HPGRSRSTSQ DDRDSEDGDQ PSPVIPVDPD ACILPDAALC AFTLLDSVLV. It is sometimes possible for the material contained within the vial of "FAAP100, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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