Rabbit anti-Human FAAP100 Polyclonal Antibody | anti-FAAP100 antibody

FAAP100 Antibody - N-terminal region

Cat. Num. AAA3215665

• Gene Names: GMPR; GMPR1; GMPR 1
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified
• Synonyms: FAAP100; Polyclonal Antibody; FAAP100 Antibody - N-terminal region; anti-FAAP100 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Affinity Purified
• Form/Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Sequence: Synthetic peptide located within the following region: HPGRSRSTSQDDRDSEDGDQPSPVIPVDPDACILPDAALCAFTLLDSVLV
• Sequence Length: 730

• Applicable Applications for anti-FAAP100 antibody: Western Blot (WB)
• Homology: Human: 100%
• Preparation and Storage: For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(WB Suggested Anti-C17orf70 AntibodyTitration: 1.0 ug/mlPositive Control: Placenta)

Related Product Information for anti-FAAP100 antibody

This is a rabbit polyclonal antibody against C17orf70. It was validated on Western Blot

Target Description: FAAP100 is a component of the Fanconi anemia (FA; MIM 277650) core complex and is required for core complex stability and FANCD2 (see MIM 227646) monoubiquitination (Ling et al., 2007 [PubMed 17396147]).[supplied by OMIM, Mar 2008]

Product Categories/Family for anti-FAAP100 antibody

Polyclonal; Drugs and Drug Metabolism; Various; DNA Repair

NCBI and Uniprot Product Information

• NCBI GI #: 156104880
• NCBI GeneID: 2766
• NCBI Accession #: NP_006868
• NCBI GenBank Nucleotide #: NM_006877
• UniProt Accession #: P36959
• Molecular Weight: 80kDa
• NCBI Official Full Name: GMP reductase 1
• NCBI Official Synonym Full Names: guanosine monophosphate reductase
• NCBI Official Symbol: GMPR
• NCBI Official Synonym Symbols: GMPR1; GMPR 1
• NCBI Protein Information: GMP reductase 1
• UniProt Protein Name: GMP reductase 1
• Protein Family: Fanconi anemia core complex-associated protein
• UniProt Gene Name: GMPR
• UniProt Synonym Gene Names: GMPR1; Guanosine monophosphate reductase 1
• UniProt Entry Name: GMPR1_HUMAN

NCBI Description

This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]

Uniprot Description

GMPR: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family.

Protein type: Nucleotide Metabolism - purine; Oxidoreductase; EC 1.7.1.7

Chromosomal Location of Human Ortholog: 6p23

Cellular Component: cytosol

Molecular Function: GMP reductase activity; metal ion binding

Biological Process: nucleobase, nucleoside and nucleotide metabolic process; nucleotide metabolic process; response to cold; purine base metabolic process; purine salvage