Western Blot (WB)
(Western Blot: Sample: Rat Liver Tissue.)
Rabbit anti-Rat Extracellular Matrix Metalloproteinase Inducer Polyclonal Antibody | anti-EMMPRIN antibody
Polyclonal Antibody to Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- EG NEPNDSCSQL WDGARLDRVH IHATYRQHAA STLSVDGLAA EDTGTYECRA SSDPDRNHLT RPPRVKWVRA QASVVVLEPG TIVTSVQEVD SKTQLTCFLN SSGIDIVGHR WMRGGKVLQE DTLPDLQMKY TVDADDRSGE YSCIFLPEPV GRGNINVEGP PRIKVGKKSE HASEGEFVKL ICKSEASHPP VDEWVWFKTS DTGDQTISNG TEANSKYVII STPELSELII SDLDMNVDPG TYVCNATNSQ
Immunocytochemistry in formalin fixed cells: 5-20ug/mL
Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL
Immunohistochemistry in paraffin section: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Rat Liver Tissue.)
Western Blot (WB)
(Western Blot: Sample: Rat Liver Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant EMMPRIN, Rat.)
Western Blot (WB)
(Western Blot: Sample: Recombinant EMMPRIN, Rat.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Heart Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Heart Tissue.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Liver Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Liver Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Stomach Tissue)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Stomach Tissue)
NCBI and Uniprot Product Information
NCBI Description
MRC OX-47 antigen that is upregulated on activated lymphocytes; member of the immunoglobulin superfamily [RGD, Feb 2006]
Uniprot Description
BSG: Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor. Forms homooligomers in a cis-dependent manner on the plasma membrane. Forms a complex with MMP1 at the tumor cell surface. Interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. Interacts with ATP1B2, MAG and L1CAM. Interacts with AJAP1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Immunoglobulin superfamily; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7q11
Cellular Component: acrosomal membrane; focal adhesion; integral component of plasma membrane; intracellular membrane-bound organelle; melanosome; membrane; membrane raft; mitochondrion; plasma membrane; sarcolemma
Molecular Function: cadherin binding; mannose binding; protein binding
Biological Process: decidualization; embryo implantation; odontogenesis of dentine-containing teeth; response to cAMP; response to mercury ion; response to peptide hormone
Research Articles on EMMPRIN
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Product Notes
The EMMPRIN bsg (Catalog #AAA2026017) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Extracellular Matrix Metalloproteinase Inducer can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-5ug/mL Immunocytochemistry in formalin fixed cells: 5-20ug/mL Immunohistochemistry in formalin fixed frozen section: 5-20ug/mL Immunohistochemistry in paraffin section: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the EMMPRIN bsg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- EG NEPNDSCSQL WDGARLDRVH IHATYRQHAA STLSVDGLAA EDTGTYECRA SSDPDRNHLT RPPRVKWVRA QASVVVLEPG TIVTSVQEVD SKTQLTCFLN SSGIDIVGHR WMRGGKVLQE DTLPDLQMKY TVDADDRSGE YSCIFLPEPV GRGNINVEGP PRIKVGKKSE HASEGEFVKL ICKSEASHPP VDEWVWFKTS DTGDQTISNG TEANSKYVII STPELSELII SDLDMNVDPG TYVCNATNSQ. It is sometimes possible for the material contained within the vial of "Extracellular Matrix Metalloproteinase Inducer, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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