SDS-Page
Extracellular Matrix Metalloproteinase Inducer Recombinant Protein | EMMPRIN recombinant protein
Recombinant Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)
Source: Prokaryotic expression
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- EG NEPNDSCSQL WDGARLDRVH IHATYRQHAA STLSVDGLAA EDTGTYECRA SSDPDRNHLT RPPRVKWVRA QASVVVLEPG TIVTSVQEVD SKTQLTCFLN SSGIDIVGHR WMRGGKVLQE DTLPDLQMKY TVDADDRSGE YSCIFLPEPV GRGNINVEGP PRIKVGKKSE HASEGEFVKL ICKSEASHPP VDEWVWFKTS DTGDQTISNG TEANSKYVII STPELSELII SDLDMNVDPG TYVCNATNSQ GSARETISLR V
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
SDS-Page
SDS-Page
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
BSG: Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor. Forms homooligomers in a cis-dependent manner on the plasma membrane. Forms a complex with MMP1 at the tumor cell surface. Interacts with SLC16A1 and SLC1A3; probably a BSG dimer is associated with a monocarboxylate transporter dimer. Interacts with ATP1B2, MAG and L1CAM. Interacts with AJAP1. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Immunoglobulin superfamily; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: Golgi membrane; focal adhesion; membrane; mitochondrion; integral to plasma membrane; plasma membrane; melanosome; sarcolemma; acrosomal membrane; lipid raft
Molecular Function: mannose binding; protein binding
Biological Process: response to peptide hormone stimulus; extracellular matrix organization and biogenesis; response to cAMP; decidualization; odontogenesis of dentine-containing teeth; response to mercury ion; extracellular matrix disassembly; cellular metabolic process; cell surface receptor linked signal transduction; blood coagulation; pyruvate metabolic process; leukocyte migration; embryo implantation
Disease: Blood Group--ok
Research Articles on EMMPRIN
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Product Notes
The EMMPRIN bsg (Catalog #AAA2030068) is a Recombinant Protein produced from Host: E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Extracellular Matrix Metalloproteinase Inducer can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the EMMPRIN bsg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.MGSSHHHHH H SSGLVPRGSH MASMTGGQQM GRGSEF- EG NEPNDSCSQL WDGARLDRVH IHATYRQHAA STLSVDGLAA EDTGTYECRA SSDPDRNHLT RPPRVKWVRA QASVVVLEPG TIVTSVQEVD SKTQLTCFLN SSGIDIVGHR WMRGGKVLQE DTLPDLQMKY TVDADDRSGE YSCIFLPEPV GRGNINVEGP PRIKVGKKSE HASEGEFVKL ICKSEASHPP VDEWVWFKTS DTGDQTISNG TEANSKYVII STPELSELII SDLDMNVDPG TYVCNATNSQ GSARETISLR V
Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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