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Western Blot (WB) (Western blot analysis of extract of various cells, using EXOC2 antibody.)

Rabbit EXOC2 Polyclonal Antibody | anti-EXOC2 antibody

EXOC2 Polyclonal Antibody

Gene Names
EXOC2; SEC5; Sec5p; SEC5L1
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Antigen Affinity Purification
Synonyms
EXOC2; Polyclonal Antibody; EXOC2 Polyclonal Antibody; SEC5; Sec5p; SEC5L1; anti-EXOC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Sequence Length
924
Applicable Applications for anti-EXOC2 antibody
Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
Recombinant protein of human EXOC2
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30285 / sc-30286
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extract of various cells, using EXOC2 antibody.)

Western Blot (WB) (Western blot analysis of extract of various cells, using EXOC2 antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
104kDa
NCBI Official Full Name
EXOC2 protein
NCBI Official Synonym Full Names
exocyst complex component 2
NCBI Official Symbol
EXOC2
NCBI Official Synonym Symbols
SEC5; Sec5p; SEC5L1
NCBI Protein Information
exocyst complex component 2
UniProt Protein Name
Exocyst complex component 2
Protein Family
UniProt Gene Name
EXOC2
UniProt Synonym Gene Names
SEC5; SEC5L1
UniProt Entry Name
EXOC2_HUMAN

NCBI Description

The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

Sec5: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 6p25.3

Cellular Component: cytosol; exocyst; intracellular membrane-bound organelle; membrane; plasma membrane

Molecular Function: protein binding; protein kinase binding; Ral GTPase binding

Biological Process: exocyst assembly

Research Articles on EXOC2

Similar Products

Product Notes

The EXOC2 exoc2 (Catalog #AAA2541607) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EXOC2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EXOC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the EXOC2 exoc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXOC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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