Testing Data
(Anti-EV71 polyprotein 3D at 1/1000 dilution)
Rabbit EV71 3D Polyclonal Antibody | anti-EV713D antibody
EV71 polyclonal 3D antibody
Reactivity
enterovirus71
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
EV71 3D; Polyclonal Antibody; EV71 polyclonal 3D antibody; 3D polymerase; Human enterovirus 71 polyprotein 3D; EV71; Enterovirus 71; anti-EV713D antibody
Host
Rabbit
Reactivity
enterovirus71
Clonality
Polyclonal
Specificity
EV71 polyclonal 3D Antibody detects endogenous levels of EV71 polyclonal 3D protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-EV713D antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from EV71 polyprotein 3D:2101-2193/2193
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Testing Data
(Anti-EV71 polyprotein 3D at 1/1000 dilution)
Testing Data
(Anti-EV71 polyprotein 3D at 1/1000 dilution)
Related Product Information for anti-EV713D antibody
Enteroviruses, such as enterovirus 71, are classified to be in the picornavirus family, pico [small] + RNA [ribonucleic acid] + virus. Picornaviruses are among the smallest and simplest ribonucleic acid containing viruses known (1). The RNA for many enteroviruses have now been cloned and complete genomic sequences have been obtained. The RNA from all sequenced enteroviruses are similar in length, about 7400 nucleotides, and have identical organization (1). The human alimentary tract is the predominant site of enterovirus replication and these viruses were first isolated from enteric specimens. These viruses are the cause of paralytic poliomyelitis, aseptic meningitis-encephalitis, myocarditis, pleurodynia, hand-foot-and-mouth disease, conjunctivitis, and numerous other syndromes associated with extra-intestinal target organs. There are 67 numbered types of enteroviruses in the enterovirus family (1): three polioviruses, twenty-three coxsackieviruses A, six coxsackieviruses B, thirty-one echoviruses, and four other enteroviruses.
NCBI and Uniprot Product Information
Uniprot Description
Capsid protein VP1: Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host cell receptor to provide virion attachment to target host cells. This attachment induces virion internalization. Tyrosine kinases are probably involved in the entry process. After binding to its receptor, the capsid undergoes conformational changes. Capsid protein VP1 N-terminus (that contains an amphipathic alpha-helix) and capsid protein VP4 are externalized. Together, they shape a pore in the host membrane through which viral genome is translocated to host cell cytoplasm. After genome has been released, the channel shrinks ().
Similar Products
Product Notes
The EV713D p2a (Catalog #AAA3013852) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EV71 polyclonal 3D antibody reacts with enterovirus71 and may cross-react with other species as described in the data sheet. AAA Biotech's EV71 3D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the EV713D p2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EV71 3D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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