Rabbit anti-Human EPR1 Polyclonal Antibody | anti-EPR1 antibody

EPR1, CT (EPR-1, Effector Cell Protease Receptor 1)

Cat. Num. AAA624363

• Gene Names: EPR1; EARLY-PHYTOCHROME-RESPONSIVE1; EPR1; F15H18.16; F15H18_16; REVEILLE 7; RVE7
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by Protein G affinity chromatography.
• Synonyms: EPR1; Polyclonal Antibody; CT (EPR-1; Effector Cell Protease Receptor 1); Anti -EPR1; anti-EPR1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human EPR1.
• Purity/Purification: Affinity Purified; Purified by Protein G affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.09% sodium azide.

• Applicable Applications for anti-EPR1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot, and Immunohistochemistry.; Dilution: ELISA: 1:1,000; Western Blot: 1:100-1:500; Immunohistochemistry: 1:50-1:100
• Immunogen: Synthetic peptide selected from the C-terminal region of human EPR1 (KLH).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(The anti-EPR1 C-term Pab is used in Western blot to detect EPR1 in HL60 cell lysate.)

Related Product Information for anti-EPR1 antibody

Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.

Product Categories/Family for anti-EPR1 antibody

Antibodies; Abs to Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 186478601
• NCBI GeneID: 838413
• NCBI Accession #: NP_001117304.1
• NCBI GenBank Nucleotide #: NM_001123832.1
• UniProt Accession #: Q8VZP5
• Molecular Weight: 38,351 Da
• NCBI Official Full Name: early-phytochrome-responsive1
• NCBI Official Symbol: EPR1
• NCBI Official Synonym Symbols: EARLY-PHYTOCHROME-RESPONSIVE1; EPR1; F15H18.16; F15H18_16; REVEILLE 7; RVE7
• NCBI Protein Information: early-phytochrome-responsive1
• UniProt Protein Name: Early-phytochrome-responsive1
• Protein Family: Proline-rich extensin-like protein
• UniProt Gene Name: EPR1
• UniProt Entry Name: Q8VZP5_ARATH

NCBI Description

EARLY-PHYTOCHROME-RESPONSIVE1

Uniprot Description

Transcription factor involved in phytochrome A-mediated cotyledon opening. Controlled by the central oscillator mediated by LHY and CCA1. Part of a regulatory circadian feedback loop. Regulates its own expression.