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Goat Eotaxin 3 Polyclonal Antibody | anti-CCL26 antibody

Eotaxin 3 antibody

Gene Names
CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
Reactivity
Human eotaxin 3
Applications
ELISA, Western Blot
Synonyms
Eotaxin 3; Polyclonal Antibody; Eotaxin 3 antibody; Polyclonal Eotaxin 3; Anti-Eotaxin 3; CCL26; Eotaxin-3; anti-CCL26 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Human eotaxin 3
Clonality
Polyclonal
Specificity
Human eotaxin 3
Form/Format
Lyophilized from PBS, pH 7.2.
Sequence Length
94
Applicable Applications for anti-CCL26 antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
Inhibition: 5-7 ug/ml
WB: 0.1-0.2 ug/ml
Biological Significance
Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL4 or IL13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology.
Immunogen
Eotaxin 3 antibody was raised in goat using highly pure recombinant human eotaxin-3 as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-CCL26 antibody
Affinity purified Goat polyclonal Eotaxin 3 antibody
Product Categories/Family for anti-CCL26 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
8.4 kDa (predicted detection band MW)
NCBI Official Full Name
eotaxin-3
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 26
NCBI Official Symbol
CCL26
NCBI Official Synonym Symbols
IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha
NCBI Protein Information
C-C motif chemokine 26
UniProt Protein Name
C-C motif chemokine 26
Protein Family
UniProt Gene Name
CCL26
UniProt Synonym Gene Names
SCYA26; MIP-4-alpha; TSC-1
UniProt Entry Name
CCL26_HUMAN

NCBI Description

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]

Uniprot Description

CCL26: Chemotactic for eosinophils and basophils. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Chemokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cell-cell signaling; positive regulation of actin filament polymerization; positive regulation of endothelial cell proliferation; immune response; signal transduction; inflammatory response; chemotaxis; positive regulation of cell migration

Research Articles on CCL26

Similar Products

Product Notes

The CCL26 ccl26 (Catalog #AAA535931) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Eotaxin 3 antibody reacts with Human eotaxin 3 and may cross-react with other species as described in the data sheet. AAA Biotech's Eotaxin 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). ELISA: 0.5-2 ug/ml Inhibition: 5-7 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the CCL26 ccl26 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Eotaxin 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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