Typical Testing Data/Standard Curve (for reference only)

Mouse Eotaxin-3 ELISA Kit | CCL26 elisa kit

Mouse Eotaxin-3 ELISA Kit

Gene Names

CCL26; IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha

Reactivity

Mouse

Synonyms

Eotaxin-3; Mouse Eotaxin-3 ELISA Kit; CCL26 elisa kit

Ordering
Cat. Num. AAA268304 For Research Use Only!

Reactivity

Mouse

Sequence Length

Samples

Mouse serum, plasma or cell culture supernatant

Assay Type

Quantitative Sandwich

Detection Range

1000 pg/mL-15.6 pg/mL

Sensitivity

Up to 5 pg/mL

Intra-assay Precision

<= 8%

Inter-assay Precision

<= 12%

Preparation and Storage

Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

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Related Product Information for CCL26 elisa kit

Principle of the Assay: As mentioned above, this kit utilizes the Double Antibody Sandwich ELISA technique. The pre-coated antibody is an anti-Mouse Eotaxin-3 monoclonal antibody, while the detection antibody is a biotinylated polyclonal antibody. Samples and biotinylated antibodies are added into ELISA plate wells and washed out with PBS or TBS after their respective additions to the wells. Then Avidin-peroxidase conjugates are added to the wells in after. TMB substrate is used for coloration after the enzyme conjugate has already been thoroughly washed out of the wells by PBS or TBS. TMB reacts to form a blue product from the peroxidase activity, and finally turns to yellow after addition of the stop solution (Color Reagent C). The color intensity and quantity of target analyte in the sample are positively correlated.

NCBI and Uniprot Product Information

NCBI GI #

4586873

NCBI GeneID

10344

Molecular Weight

10,648 Da

NCBI Official Full Name

eotaxin-3

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 26

NCBI Official Symbol

CCL26

NCBI Official Synonym Symbols

IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha

NCBI Protein Information

C-C motif chemokine 26; eotaxin-3; MIP-4-alpha; chemokine N1; CC chemokine IMAC; thymic stroma chemokine-1; small inducible cytokine A26; small-inducible cytokine A26; macrophage inflammatory protein 4-alpha; small inducible cytokine subfamily A (Cys-Cys), member 26

UniProt Protein Name

C-C motif chemokine 26

Protein Family

C-C motif chemokine

UniProt Gene Name

CCL26

UniProt Synonym Gene Names

SCYA26; UNQ216/PRO242; MIP-4-alpha; TSC-1

UniProt Entry Name

CCL26_HUMAN

NCBI Description

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]

Uniprot Description

CCL26: Chemotactic for eosinophils and basophils. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Chemokine; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cell-cell signaling; positive regulation of actin filament polymerization; immune response; positive regulation of endothelial cell proliferation; inflammatory response; chemotaxis; signal transduction; positive regulation of cell migration

Research Articles on CCL26

1. CCL11, CCL24, and CCL26 are increased in TB patients; hence, it seems that TB suppresses Th1 and the classic function of macrophages subsequently by inducing the chemokines' expression

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Product Notes

The Mouse CCL26 ccl26 (Catalog #AAA268304) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA268304 ELISA Kit recognizes Mouse CCL26. It is sometimes possible for the material contained within the vial of "Eotaxin-3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Mouse Eotaxin-3 ELISA Kit | CCL26 elisa kit