Western Blot (WB)
Rabbit Endoplasmic reticulum resident protein 29 Polyclonal Antibody | anti-ERP29 antibody
Endoplasmic reticulum resident protein 29 Polyclonal Antibody
Gene Names
ERP29; ERp28; ERp31; PDIA9; PDI-DB; C12orf8; HEL-S-107
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig
Applications
Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Endoplasmic reticulum resident protein 29; Polyclonal Antibody; Endoplasmic reticulum resident protein 29 Polyclonal Antibody; ERP29; anti-ERP29 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Endoplasmic reticulum resident protein 29 polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
53
Applicable Applications for anti-ERP29 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Endoplasmic reticulum resident protein 29 protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Western Blot (WB)
Western Blot (WB)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embeded human liver using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embeded human liver using at dilution of 1:100.)
Related Product Information for anti-ERP29 antibody
Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells.Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI¡¯s thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.
Product Categories/Family for anti-ERP29 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
5,477 Da
NCBI Official Full Name
endoplasmic reticulum resident protein 29 isoform 2
NCBI Official Synonym Full Names
endoplasmic reticulum protein 29
NCBI Official Symbol
ERP29
NCBI Official Synonym Symbols
ERp28; ERp31; PDIA9; PDI-DB; C12orf8; HEL-S-107
NCBI Protein Information
endoplasmic reticulum resident protein 29
UniProt Protein Name
Endoplasmic reticulum resident protein 29
Protein Family
UniProt Gene Name
ERP29
UniProt Synonym Gene Names
C12orf8; ERP28; ERp29; ERp28; ERp31
UniProt Entry Name
ERP29_HUMAN
Uniprot Description
ERP29: Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 12q24.13
Cellular Component: cell surface; endoplasmic reticulum; membrane; smooth endoplasmic reticulum; transport vesicle
Molecular Function: chaperone binding; protein disulfide isomerase activity; protein homodimerization activity
Biological Process: activation of MAPK activity; intracellular protein transport; negative regulation of protein secretion; positive regulation of protein amino acid phosphorylation
Similar Products
Product Notes
The ERP29 erp29 (Catalog #AAA9415071) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Endoplasmic reticulum resident protein 29 Polyclonal Antibody reacts with Human, Mouse, Rat, Cow, Dog, Guinea Pig and may cross-react with other species as described in the data sheet. AAA Biotech's Endoplasmic reticulum resident protein 29 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: 1:500 - 1:1000 Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the ERP29 erp29 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Endoplasmic reticulum resident protein 29, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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