Rabbit anti-Human EML1 Polyclonal Antibody | anti-EML1 antibody

EML1 antibody

Cat. Num. AAA9403795

• Gene Names: EML1; EMAP; ELP79; EMAPL; HuEMAP
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by antigen-affinity chromatography.
• Synonyms: EML1; Polyclonal Antibody; EML1 antibody; anti-EML1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified by antigen-affinity chromatography.
• Form/Format: Supplied in 1XPBS, 1%BSA, 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
• Sequence Length: 834

• Applicable Applications for anti-EML1 antibody: Western Blot (WB)
• Application Notes: Western blotting: 1:500-1:3000
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide contain a sequence corresponding to a region within amino acids 772 and 834 of EML1
• Target Name: EML1
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE EML1 antibody diluted at 1: 500)

Related Product Information for anti-EML1 antibody

Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Product Categories/Family for anti-EML1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 56790932
• NCBI GeneID: 2009
• NCBI Accession #: NP_001008707
• NCBI GenBank Nucleotide #: NM_001008707.1
• Molecular Weight: 91,985 Da
• NCBI Official Full Name: echinoderm microtubule-associated protein-like 1 isoform a
• NCBI Official Synonym Full Names: echinoderm microtubule associated protein like 1
• NCBI Official Symbol: EML1
• NCBI Official Synonym Symbols: EMAP; ELP79; EMAPL; HuEMAP
• NCBI Protein Information: echinoderm microtubule-associated protein-like 1
• UniProt Protein Name: Echinoderm microtubule-associated protein-like 1
• Protein Family: Echinoderm microtubule-associated protein
• UniProt Gene Name: EML1
• UniProt Synonym Gene Names: EMAP1; EMAPL; EMAPL1; EMAP-1; HuEMAP-1
• UniProt Entry Name: EMAL1_HUMAN

NCBI Description

Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

EML1: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic. Belongs to the WD repeat EMAP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; Cytoskeletal

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: microtubule; microtubule associated complex; perinuclear region of cytoplasm; cytosol

Molecular Function: tubulin binding; protein binding; microtubule binding; calcium ion binding

Biological Process: mitotic spindle organization and biogenesis; neuroblast proliferation; hemopoietic progenitor cell differentiation; brain development; microtubule cytoskeleton organization and biogenesis