Rabbit anti-Human, Mouse ELOVL7 Polyclonal Antibody | anti-ELOVL7 antibody

ELOVL7, CT (ELOVL7, Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase ELOVL7, ELOVL fatty acid elongase 7) (Azide free) (HRP)

Cat. Num. AAA6295417

• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ELOVL7; Polyclonal Antibody; CT (ELOVL7; Elongation of very long chain fatty acids protein 7; 3-keto acyl-CoA synthase ELOVL7; ELOVL fatty acid elongase 7) (Azide free) (HRP); ELOVL fatty acid elongase 7; anti-ELOVL7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Sequence Length: 281

• Applicable Applications for anti-ELOVL7 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ELOVL7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-273 amino acids from the C-terminal region of human ELOVL7.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ELOVL7 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the ELOVL7 antibody detected the ELOVL7 protein (arrow).)

Related Product Information for anti-ELOVL7 antibody

ELOVL7 could be implicated in synthesis of very long chain fatty acids and sphingolipids (By similarity).

Product Categories/Family for anti-ELOVL7 antibody

Antibodies; Enzymes; Synthase

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Tamura, K., et al. Cancer Res. 69(20):8133-8140(2009). Lehner, R., et al. Prog. Lipid Res. 35(2):169-201(1996).

NCBI and Uniprot Product Information

• NCBI GI #: 157388947
• NCBI GeneID: 79993
• NCBI Accession #: NP_079206.2
• NCBI GenBank Nucleotide #: NP_079206.2
• UniProt Accession #: A1L3X0
• NCBI Official Full Name: elongation of very long chain fatty acids protein 7 isoform 1
• NCBI Official Synonym Full Names: ELOVL fatty acid elongase 7
• NCBI Official Symbol: ELOVL7
• NCBI Protein Information: elongation of very long chain fatty acids protein 7
• UniProt Protein Name: Elongation of very long chain fatty acids protein 7
• Protein Family: Elongation of very long chain fatty acids protein
• UniProt Gene Name: ELOVL7
• UniProt Synonym Gene Names: ELOVL FA elongase 7
• UniProt Entry Name: ELOV7_HUMAN

Uniprot Description

ELOVL7: Condensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. Belongs to the ELO family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; EC 2.3.1.199

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: transferase activity; protein binding

Biological Process: very-long-chain fatty acid biosynthetic process; triacylglycerol biosynthetic process; fatty acid elongation, saturated fatty acid; cellular lipid metabolic process