Rabbit anti-Human, Mouse ELOVL7 Polyclonal Antibody | anti-ELOVL7 antibody

ELOVL7 Antibody

Cat. Num. AAA9401717

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity chromatography purified via peptide column
• Synonyms: ELOVL7; Polyclonal Antibody; ELOVL7 Antibody; Elongation of very long chain fatty acids protein 7; anti-ELOVL7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Purity/Purification: Affinity chromatography purified via peptide column
• Form/Format: Supplied in PBS containing 0.02% sodium azide.
• Sequence Length: 281

• Applicable Applications for anti-ELOVL7 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen Type: Peptide
• Immunogen Description: Raised against a 15 amino acid peptide near the amino terminus of human ELOVL7.
• Target Name: ELOVL7
• Preparation and Storage: Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of ELOVL7 in human liver tissue lysate with ELOVL7 antibody at 1 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of ELOVL7 in human liver tissue with ELOVL7 antibody at 5 ug/mL.)

Related Product Information for anti-ELOVL7 antibody

Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.

Product Categories/Family for anti-ELOVL7 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 157388949
• NCBI GeneID: 79993
• NCBI Accession #: NP_001098028
• NCBI GenBank Nucleotide #: NM_001104558.1
• Molecular Weight: 33,356 Da
• NCBI Official Full Name: elongation of very long chain fatty acids protein 7 isoform 1
• NCBI Official Synonym Full Names: ELOVL fatty acid elongase 7
• NCBI Official Symbol: ELOVL7
• NCBI Protein Information: elongation of very long chain fatty acids protein 7
• UniProt Protein Name: Elongation of very long chain fatty acids protein 7
• Protein Family: Elongation of very long chain fatty acids protein
• UniProt Gene Name: ELOVL7
• UniProt Synonym Gene Names: ELOVL FA elongase 7
• UniProt Entry Name: ELOV7_HUMAN

Uniprot Description

ELOVL7: Condensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. Belongs to the ELO family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; EC 2.3.1.199

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: transferase activity; protein binding

Biological Process: very-long-chain fatty acid biosynthetic process; triacylglycerol biosynthetic process; fatty acid elongation, saturated fatty acid; cellular lipid metabolic process