Rabbit anti-Human ELOVL1 Polyclonal Antibody | anti-ELOVL1 antibody
ELOVL1, NT (ELOVL1, SSC1, Elongation of very long chain fatty acids protein 1, 3-keto acyl-CoA synthase ELOVL1, ELOVL fatty acid elongase 1) (MaxLight 550)
Gene Names
ELOVL1; Ssc1; CGI-88
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
ELOVL1; Polyclonal Antibody; NT (ELOVL1; SSC1; Elongation of very long chain fatty acids protein 1; 3-keto acyl-CoA synthase ELOVL1; ELOVL fatty acid elongase 1) (MaxLight 550); ELOVL fatty acid elongase 1; anti-ELOVL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Applicable Applications for anti-ELOVL1 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
ELOVL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ELOVL1.
Conjugate
MaxLight550
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for anti-ELOVL1 antibody
ELOVL1 could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative (By similarity).
Product Categories/Family for anti-ELOVL1 antibody
References
Ohno, Y., et al. Proc. Natl. Acad. Sci. U.S.A. 107(43):18439-18444(2010). Ofman, R., et al. EMBO Mol Med 2(3):90-97(2010). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Lehner, R., et al. Prog. Lipid Res. 35(2):169-201(1996).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,485 Da
NCBI Official Full Name
elongation of very long chain fatty acids protein 1 isoform 1
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 1
NCBI Official Symbol
ELOVL1
NCBI Official Synonym Symbols
Ssc1; CGI-88
NCBI Protein Information
elongation of very long chain fatty acids protein 1
UniProt Protein Name
Elongation of very long chain fatty acids protein 1
Protein Family
UniProt Gene Name
ELOVL1
UniProt Synonym Gene Names
SSC1; ELOVL FA elongase 1
UniProt Entry Name
ELOV1_HUMAN
Uniprot Description
ELOVL1: Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Belongs to the ELO family.
Protein type: EC 2.3.1.199; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p34.2
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to endoplasmic reticulum membrane
Molecular Function: protein binding; fatty acid elongase activity
Biological Process: sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; fatty acid elongation, saturated fatty acid
Research Articles on ELOVL1
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Product Notes
The ELOVL1 elovl1 (Catalog #AAA6295354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ELOVL1, NT (ELOVL1, SSC1, Elongation of very long chain fatty acids protein 1, 3-keto acyl-CoA synthase ELOVL1, ELOVL fatty acid elongase 1) (MaxLight 550) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ELOVL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the ELOVL1 elovl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELOVL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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