Rabbit ELOVL1 Polyclonal Antibody | anti-ELOVL1 antibody
ELOVL1 Antibody BIOTIN-Conjugated
Gene Names
ELOVL1; Ssc1; CGI-88
Reactivity
Human, Monkey
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
ELOVL1; Polyclonal Antibody; ELOVL1 Antibody BIOTIN-Conjugated; 3 keto acyl CoA synthase ELOVL1; CGI 88; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1; Elongation of very long chain fatty acids protein 1; ELOVL 1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; Ssc1; Very-long-chain 3-oxoacyl-CoA synthase 1 antibody; anti-ELOVL1 antibody
Host
Rabbit
Reactivity
Human, Monkey
Clonality
Polyclonal
Form/Format
BIOTIN-Conjugated
Concentration
0.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
198
Applicable Applications for anti-ELOVL1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:10,000
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500
Immunogen
Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
Immunoglobulin
IgG
Expression
Ubiquitous
Molecular Function
Transferase; Fatty acid biosynthesis & metabolism; Lipid biosynthesis & metabolism
Structure
The di-lysine motif may confer endoplasmic reticulum localization.
Subcellular Location
Endoplasmic Reticulum membrane; Multi-pass membrane protein
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-ELOVL1 antibody
BIOTIN-Conjugated Elongation of very long chain fatty acids protein 1 Antibody
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,485 Da
NCBI Official Full Name
elongation of very long chain fatty acids protein 1 isoform 3
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 1
NCBI Official Symbol
ELOVL1
NCBI Official Synonym Symbols
Ssc1; CGI-88
NCBI Protein Information
elongation of very long chain fatty acids protein 1
UniProt Protein Name
Elongation of very long chain fatty acids protein 1
Protein Family
UniProt Gene Name
ELOVL1
UniProt Synonym Gene Names
ELOVL FA elongase 1
UniProt Entry Name
ELOV1_HUMAN
Uniprot Description
ELOVL1: Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Belongs to the ELO family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.199
Chromosomal Location of Human Ortholog: 1p34.2
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; membrane
Molecular Function: fatty acid elongase activity; protein binding
Biological Process: fatty acid elongation, saturated fatty acid; linoleic acid metabolic process; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process
Research Articles on ELOVL1
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Product Notes
The ELOVL1 elovl1 (Catalog #AAA541486) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ELOVL1 Antibody BIOTIN-Conjugated reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's ELOVL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:10,000 Immunohistochemistry: 1:100 Immunoprecipitation: 1:200 Western Blot: 1:500. Researchers should empirically determine the suitability of the ELOVL1 elovl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELOVL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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