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Western Blot (WB) (Western blot analysis of ELL Antibody (C-term) in mouse testis tissue lysates (35ug/lane). ELL (arrow) was detected using the purified Pab.)

Rabbit anti-Human, mouse ELL Polyclonal Antibody | anti-ELL antibody

ELL Antibody (C-term)

Gene Names
ELL; MEN; ELL1; PPP1R68; C19orf17
Reactivity
Human, mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ELL; Polyclonal Antibody; ELL Antibody (C-term); RNA polymerase II elongation factor ELL; Eleven-nineteen lysine-rich leukemia protein; C19orf17; anti-ELL antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ELL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human ELL.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.35 (varies by lot)
Sequence Positions
516-545
Sequence Length
621
Applicable Applications for anti-ELL antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of ELL Antibody (C-term) in mouse testis tissue lysates (35ug/lane). ELL (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of ELL Antibody (C-term) in mouse testis tissue lysates (35ug/lane). ELL (arrow) was detected using the purified Pab.)
Related Product Information for anti-ELL antibody
Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
References
Zhou, J., et al. J. Biol. Chem. 284(28):19142-19152(2009)
?Jiang, F., et al. Cancer Lett. 253(2):265-272(2007)
?Matsuoka, S., et al. Science 316(5828):1160-1166(2007)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68265
NCBI Official Full Name
RNA polymerase II elongation factor ELL
NCBI Official Synonym Full Names
elongation factor RNA polymerase II
NCBI Official Symbol
ELL
NCBI Official Synonym Symbols
MEN; ELL1; PPP1R68; C19orf17
NCBI Protein Information
RNA polymerase II elongation factor ELL
UniProt Protein Name
RNA polymerase II elongation factor ELL
Protein Family
UniProt Gene Name
ELL
UniProt Synonym Gene Names
C19orf17
UniProt Entry Name
ELL_HUMAN

Uniprot Description

ELL: Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. A chromosomal aberration involving ELL is found in acute leukemias. Translocation t(11;19)(q23;p13.1) with MLL/HRX. The result is a rogue activator protein. Belongs to the ELL/occludin family.

Protein type: Transcription initiation complex; Oncoprotein; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: nucleoplasm; Cajal body; transcription elongation factor complex; nuclear speck

Molecular Function: protein binding; phosphatase binding

Biological Process: transcription from RNA polymerase II promoter; viral reproduction; in utero embryonic development; positive regulation of RNA elongation from RNA polymerase II promoter; positive regulation of viral transcription; positive regulation of RNA elongation; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase III promoter; gene expression; snRNA transcription from RNA polymerase III promoter

Research Articles on ELL

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Product Notes

The ELL ell (Catalog #AAA9206091) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 516-545. The ELL Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ELL can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the ELL ell for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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