Rabbit anti-Mouse Elastase 1, Pancreatic (ELA1) Polyclonal Antibody | anti-ELA1 antibody
Biotin-Linked Polyclonal Antibody to Elastase 1, Pancreatic (ELA1)
Immunohistochemistry: 5-20 ug/mL;1:30-120
Immunocytochemistry: 5-20 ug/mL;1:30-120
Optimal working dilutions must be determined by end user
Store at 4 degree C for frequent use.
Aliquot and store at -20°C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
NCBI and Uniprot Product Information
NCBI Description
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]
Uniprot Description
CELA1: Acts upon elastin. Belongs to the peptidase S1 family. Elastase subfamily.
Protein type: EC 3.4.21.36; Protease; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: extracellular space
Molecular Function: metal ion binding; serine-type endopeptidase activity
Biological Process: exocrine pancreas development; inflammatory response; multicellular organism growth; negative regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; proteolysis; regulation of cell differentiation; regulation of cell proliferation; tissue remodeling; Wnt signaling pathway
Research Articles on ELA1
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Product Notes
The ELA1 cela1 (Catalog #AAA2093372) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Biotin-Linked Polyclonal Antibody to Elastase 1, Pancreatic (ELA1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Elastase 1, Pancreatic (ELA1) can be used in a range of immunoassay formats including, but not limited to, WB; IHC; ICC; IP. Western blotting: 0.5-2 ug/mL;1:300-1200 Immunohistochemistry: 5-20 ug/mL;1:30-120 Immunocytochemistry: 5-20 ug/mL;1:30-120 Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the ELA1 cela1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Elastase 1, Pancreatic (ELA1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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