Rabbit anti-Human EIF5AL1 Polyclonal Antibody | anti-EIF5AL1 antibody

EIF5AL1, CT (EIF5AL1, Eukaryotic translation initiation factor 5A-1-like, Eukaryotic initiation factor 5A isoform 1-like)

Cat. Num. AAA6009462

• Gene Names: EIF5AL1; EIF5AP1; bA342M3.3
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: EIF5AL1; Polyclonal Antibody; CT (EIF5AL1; Eukaryotic translation initiation factor 5A-1-like; Eukaryotic initiation factor 5A isoform 1-like); Anti -EIF5AL1; anti-EIF5AL1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-EIF5AL1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Immunohistochemistry: 1:10-50; Immunofluorescence: 1:10-50
• Immunogen: EIF5AL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the C-terminal region of human EIF5AL1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(EIF5AL1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF5AL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Western Blot (WB)

(EIF5AL1 Antibody (C-term) western blot analysis in Ramos,A2058 cell line lysates (35ug/lane).This demonstrates the EIF5AL1 antibody detected the EIF5AL1 protein (arrow).)

Immunofluorescence (IF)

(Confocal immunofluorescent analysis of EIF5AL1 Antibody (C-term) with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)

Related Product Information for anti-EIF5AL1 antibody

EIF5AL1is a mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity).

Product Categories/Family for anti-EIF5AL1 antibody

Antibodies; Abs to Translation Initiation Factors

NCBI and Uniprot Product Information

• NCBI GI #: 153791632
• NCBI GeneID: 143244
• NCBI Accession #: NP_001093162.1
• NCBI GenBank Nucleotide #: NM_001099692.1
• UniProt Accession #: Q6IS14
• Molecular Weight: 16,773 Da
• NCBI Official Full Name: eukaryotic translation initiation factor 5A-1-like
• NCBI Official Synonym Full Names: eukaryotic translation initiation factor 5A-like 1
• NCBI Official Symbol: EIF5AL1
• NCBI Official Synonym Symbols: EIF5AP1; bA342M3.3
• NCBI Protein Information: eukaryotic translation initiation factor 5A-1-like; eukaryotic translation initiation factor 5A pseudogene 1
• UniProt Protein Name: Eukaryotic translation initiation factor 5A-1-like
• Protein Family: Eukaryotic translation initiation factor
• UniProt Gene Name: EIF5AL1
• UniProt Synonym Gene Names: eIF-5A-1-like
• UniProt Entry Name: IF5AL_HUMAN

Uniprot Description

EIF5AL1: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Belongs to the eIF-5A family.

Chromosomal Location of Human Ortholog: 10q22.3

Cellular Component: endoplasmic reticulum membrane; nuclear pore

Molecular Function: ribosome binding; translation elongation factor activity

Biological Process: protein transport; translational frameshifting; mRNA transport; positive regulation of translational elongation; positive regulation of translational termination