Rabbit EIF2S3 Polyclonal Antibody | anti-EIF2S3 antibody

EIF2S3 Rabbit Polyclonal

Cat. Num. AAA768933

• Gene Names: EIF2S3; EIF2; EIF2G; eIF-2gA; EIF2gamma
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: EIF2S3; Polyclonal Antibody; EIF2S3 Rabbit Polyclonal; EIF2G; anti-EIF2S3 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human, Rat; Other species are not tested. Please decide the specificity by homology
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid; PBS with 0.02% sodium azide and 50% glycerol pH 7.3
• Sequence Length: 472

• Applicable Applications for anti-EIF2S3 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Immunogen: eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
• Preparation and Storage: -20 degree C for 12 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human stomach using MBS768933 (EIF2S3 antibody) at dilution of 1:50)

Western Blot (WB)

(HeLa cells were subjected to SDS PAGE followed by western blot with MBS768933 (EIF2S3 antibody) at dilution of 1:1000)

Related Product Information for anti-EIF2S3 antibody

The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit.

NCBI and Uniprot Product Information

• NCBI GI #: 4503507
• NCBI GeneID: 1968
• NCBI Accession #: NP_001406.1
• NCBI GenBank Nucleotide #: NM_001415.3
• UniProt Accession #: P41091; Q53HK3; A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4
• Molecular Weight: 45 kDa
• NCBI Official Full Name: eukaryotic translation initiation factor 2 subunit 3
• NCBI Official Synonym Full Names: eukaryotic translation initiation factor 2 subunit gamma
• NCBI Official Symbol: EIF2S3
• NCBI Official Synonym Symbols: EIF2; EIF2G; eIF-2gA; EIF2gamma
• NCBI Protein Information: eukaryotic translation initiation factor 2 subunit 3
• UniProt Protein Name: Eukaryotic translation initiation factor 2 subunit 3
• Protein Family: Eukaryotic translation initiation factor
• UniProt Gene Name: EIF2S3
• UniProt Synonym Gene Names: EIF2G; eIF-2-gamma X; eIF-2gX
• UniProt Entry Name: IF2G_HUMAN

NCBI Description

The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]

Uniprot Description

eIF2-gamma: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: Xp22.2-p22.1

Cellular Component: cytoplasm; cytosol; nucleus

Molecular Function: GTP binding; GTPase activity; protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity

Biological Process: formation of translation preinitiation complex; translational initiation; transmembrane transport