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Rabbit EIF2B3 Polyclonal Antibody | anti-EIF2B3 antibody

EIF2B3

Gene Names
EIF2B3; EIF-2B; EIF2Bgamma
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
EIF2B3; Polyclonal Antibody; EIF-2B; EIF2Bgamma; anti-EIF2B3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
1580
Applicable Applications for anti-EIF2B3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 201-357aa of human EIF2B3.
Cellular Localization
Cytoplasm
Related Product Information for anti-EIF2B3 antibody
Homo sapiens eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa (EIF2B3), transcrip
References
La Piana R, Vanderver A, van der Knaap M. et al. Adult-onset vanishing white matter disease due to a novel EIF2B3 mutation. Arch Neurol. 69(6):765-8 (2012)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
49KD
NCBI Official Full Name
Homo sapiens eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa, mRNA
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 2B subunit gamma
NCBI Official Symbol
EIF2B3
NCBI Official Synonym Symbols
EIF-2B; EIF2Bgamma
NCBI Protein Information
translation initiation factor eIF-2B subunit gamma

NCBI Description

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Research Articles on EIF2B3

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Product Notes

The EIF2B3 (Catalog #AAA8560936) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EIF2B3 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EIF2B3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-80,000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the EIF2B3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EIF2B3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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