Western Blot (WB)
(Mouse Eif2ak4 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Eif2ak4 antibody detected the Eif2ak4 protein (arrow).)
Rabbit anti-Mouse Eif2ak4 Polyclonal Antibody | anti-Eif2ak4 antibody
Mouse Eif2ak4 Antibody (C-term)
Western Blot (WB)
(Mouse Eif2ak4 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Eif2ak4 antibody detected the Eif2ak4 protein (arrow).)
Western Blot (WB)
(Mouse Eif2ak4 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Eif2ak4 antibody detected the Eif2ak4 protein (arrow).)
Immunohistochemistry (IHC)
(Mouse Eif2ak4 Antibody (C-term) (MBS9204038)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse live tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Eif2ak4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Mouse Eif2ak4 Antibody (C-term) (MBS9204038)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse live tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Eif2ak4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Ye, J., et al. EMBO J. 29(12):2082-2096(2010)
Liu, Y., et al. Neoplasia 12(1):61-68(2010)
Jasperson, L.K., et al. Blood 114(24):5062-5070(2009)
Bunpo, P., et al. J. Biol. Chem. 284(47):32742-32749(2009)
NCBI and Uniprot Product Information
Uniprot Description
GCN2: a kinase of the PEK family. Phosphorylates and inhibits eukaryotic initiation factor (eIF)-2 alpha, providing an important protective mechanism during various cellular stress conditions including endoplasmic reticulum (ER) stress.
Protein type: EC 2.7.11.1; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Translation; Kinase, protein; Other group; PEK family; GCN2 subfamily
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein homodimerization activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; eukaryotic translation initiation factor 2alpha kinase activity; ATP binding; protein kinase activity
Biological Process: regulation of translation initiation in response to stress; unfolded protein response; negative regulation of translation; cellular response to starvation; protein amino acid phosphorylation; phosphorylation; regulation of translational initiation
Research Articles on Eif2ak4
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Product Notes
The Eif2ak4 eif2ak4 (Catalog #AAA9204038) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1477-1504. The Mouse Eif2ak4 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Eif2ak4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the Eif2ak4 eif2ak4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Eif2ak4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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