Rabbit EGR2 Polyclonal Antibody | anti-EGR2 antibody
EGR2 Antibody BIOTIN
Gene Names
Egr2; Egr-2; Zfp-6; Krox20; NGF1-B; Zfp-25; Krox-20
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Purity
Immobilized antigen affinity chromatography
Synonyms
EGR2; Polyclonal Antibody; EGR2 Antibody BIOTIN; BIOTIN-Conjugated E3 SUMO-protein ligase EGR2/KROX20 Antibody; AT591 antibody; CMT1D antibody; CMT4E antibody; E3 SUMO-protein ligase EGR2 antibody; Early growth response 2 antibody; EGR-2 antibody; FLJ14547 antibody; KROX 20 Drosophila homolog antibody; KROX20 antibody; Zinc finger protein Krox-20 antibody; anti-EGR2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immobilized antigen affinity chromatography
Concentration
0.5-1.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
420
Applicable Applications for anti-EGR2 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
ELISA: 1:50,000
IP: 1:200
WB: 1:2,500-1:5,000
IP: 1:200
WB: 1:2,500-1:5,000
Immunogen
Synthetic peptide taken within amino acid region 60-150 on mouse E3 SUMO-protein ligase EGR2.
Conjugation
BIOTIN
Molecular Function
chromatin binding; DNA binding; HMG box domain binding; ligase activity; metal ion binding; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; transcriptional activator activ
Subcellular Location
Nucleus
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for anti-EGR2 antibody
Overview: Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.
Structure: Belongs to the EGR C2H2-type zinc-finger protein family.
Expression: Expressed in mammary tumors (at protein level). Expressed mainly in adult thymus and embryonic nervous system.
Structure: Belongs to the EGR C2H2-type zinc-finger protein family.
Expression: Expressed in mammary tumors (at protein level). Expressed mainly in adult thymus and embryonic nervous system.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,500 Da
NCBI Official Full Name
E3 SUMO-protein ligase EGR2 isoform 2
NCBI Official Synonym Full Names
early growth response 2
NCBI Official Symbol
Egr2
NCBI Official Synonym Symbols
Egr-2; Zfp-6; Krox20; NGF1-B; Zfp-25; Krox-20
NCBI Protein Information
E3 SUMO-protein ligase EGR2
UniProt Protein Name
E3 SUMO-protein ligase EGR2
Protein Family
UniProt Gene Name
Egr2
UniProt Synonym Gene Names
Egr-2; Krox-20; Zfp-25; EGR-2
Uniprot Description
Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. Binds to the promoter region of ERBB2. May play a role in the regulation of hindbrain segmentation, might act in combination with the Hox network to specify odd and even rhombomeres, and might participate in the control of the expression of some of the homeobox containing genes.
Research Articles on EGR2
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Product Notes
The EGR2 egr2 (Catalog #AAA5400463) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EGR2 Antibody BIOTIN reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EGR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). ELISA: 1:50,000 IP: 1:200 WB: 1:2,500-1:5,000. Researchers should empirically determine the suitability of the EGR2 egr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EGR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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