Western Blot (WB)
(Western blot analysis of EFCAB4A in human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 μg/mL.)
Rabbit EFCAB4A Polyclonal Antibody | anti-EFCAB4A antibody
EFCAB4A Antibody
Gene Names
CRACR2B; EFCAB4A
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
EFCAB4A Antibody is affinity chromatography purified via peptide column.
Synonyms
EFCAB4A; Polyclonal Antibody; EFCAB4A Antibody; CRACR2B; EF-hand calcium-binding domain-containing protein 4A; Calcium release-activated calcium channel regulator 2B; CRAC channel regulator 2B; EF-hand calcium binding domain 4A; anti-EFCAB4A antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
EFCAB4A Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
294
Applicable Applications for anti-EFCAB4A antibody
ELISA (EIA), Western Blot (WB)
Application Notes
EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A.
Buffer
EFCAB4A Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
EFCAB4A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of EFCAB4A in human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 μg/mL.)
Western Blot (WB)
(Western blot analysis of EFCAB4A in human lung tissue lysate with EFCAB4A antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-EFCAB4A antibody
EFCAB4A Antibody: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,746 Da
NCBI Official Full Name
EF-hand calcium-binding domain-containing protein 4A isoform 2
NCBI Official Synonym Full Names
calcium release activated channel regulator 2B
NCBI Official Symbol
CRACR2B
NCBI Official Synonym Symbols
EFCAB4A
NCBI Protein Information
EF-hand calcium-binding domain-containing protein 4A; CRAC regulator 2B; CRAC channel regulator 2B; EF-hand calcium binding domain 4A; calcium release-activated channel regulator 2B; calcium release-activated calcium channel regulator 2B; Ca2+ release-activated Ca2+ (CRAC) channel regulator 2B
UniProt Protein Name
EF-hand calcium-binding domain-containing protein 4A
UniProt Gene Name
CRACR2B
UniProt Synonym Gene Names
EFCAB4A; CRAC channel regulator 2B
UniProt Entry Name
EFC4A_HUMAN
Uniprot Description
EFCAB4A: Plays a role in store-operated Ca(2+) entry (SOCE). Belongs to the EFCAB4 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 11p15.5
Cellular Component: cytoplasm
Molecular Function: calcium ion binding
Similar Products
Product Notes
The EFCAB4A cracr2b (Catalog #AAA150604) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EFCAB4A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EFCAB4A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the EFCAB4A cracr2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EFCAB4A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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