Western Blot (WB)
(Western Blot analysis of extract of various cells, using DYNC2LI1 antibody.)
Rabbit DYNC2LI1 Polyclonal Antibody | anti-DYNC2LI1 antibody
DYNC2LI1 Polyclonal Antibody
Gene Names
DYNC2LI1; LIC3; D2LIC; CGI-60
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
DYNC2LI1; Polyclonal Antibody; DYNC2LI1 Polyclonal Antibody; LIC3; D2LIC; CGI-60; anti-DYNC2LI1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
DYNC2LI1 polyclonal antibody detects endogenous levels of DYNC2LI1 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
352
Applicable Applications for anti-DYNC2LI1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human DYNC2LI1.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extract of various cells, using DYNC2LI1 antibody.)
Western Blot (WB)
(Western Blot analysis of extract of various cells, using DYNC2LI1 antibody.)
Related Product Information for anti-DYNC2LI1 antibody
DYNC2LI1 (dynein, cytoplasmic 2, light intermediate chain 1), also known as LIC3, D2LIC or CGI-60, is a 351 amino acid cytoplasmic protein belonging to the dynein light intermediate chain family. DYNC2LI1 may function as a motor for intraflagellar retrograde transport and in cilia biogenesis. The cytoplasmic dynein complex 2 may be composed of a DYNC2H1 homodimer and a number of DYNC2LI1 light intermediate chains. DYNC2LI1 exists as five alternatively spliced isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 40kDa
NCBI Official Full Name
cytoplasmic dynein 2 light intermediate chain 1 isoform 4
NCBI Official Synonym Full Names
dynein cytoplasmic 2 light intermediate chain 1
NCBI Official Symbol
DYNC2LI1
NCBI Official Synonym Symbols
LIC3; D2LIC; CGI-60
NCBI Protein Information
cytoplasmic dynein 2 light intermediate chain 1
UniProt Protein Name
Cytoplasmic dynein 2 light intermediate chain 1
Protein Family
UniProt Gene Name
DYNC2LI1
UniProt Synonym Gene Names
D2LIC; LIC3; CGI-60; Dynein 2 light intermediate chain
UniProt Entry Name
DC2L1_HUMAN
NCBI Description
This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Research Articles on DYNC2LI1
Similar Products
Product Notes
The DYNC2LI1 dync2li1 (Catalog #AAA3008630) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYNC2LI1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DYNC2LI1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the DYNC2LI1 dync2li1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYNC2LI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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