Western Blot (WB)
(Western Blot analysis of 30ug of total cell lysate from Jurkat (lane 1), HeLa (lane 2), and Daudi (lane 3) cells with MBS617983 at 2 ug/ml.)
Rabbit anti-Human DR6 Polyclonal Antibody | anti-DR6 antibody
DR6 (Death Receptor6)
Reactivity
Human
Applications
Western Blot
Purity
PurifiedPurified
Synonyms
DR6; Polyclonal Antibody; DR6 (Death Receptor6); Anti -DR6 (Death Receptor6); anti-DR6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human DR6 (Death Receptor6)
Purity/Purification
Purified
Purified
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Applicable Applications for anti-DR6 antibody
Western Blot (WB)
Application Notes
Suitable for the detection of DR6 expression by Western blot. Whole cell lysate from Jurkat, Daudi and HeLa cells can be used as positive control and approximately 66kD is detected. Western blot analysis of 30ug of total cell lysate from Jurkat (lane 1), HeLa (lane 2), and Daudi (lane 3) cells with antibody at 2ug/ml.
Dilution: Western blot: 2-4ug/ml
Dilution: Western blot: 2-4ug/ml
Immunogen
Cytoplasmic domain (amino acids 371-655) of human DR6 protein.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Western Blot (WB)
(Western Blot analysis of 30ug of total cell lysate from Jurkat (lane 1), HeLa (lane 2), and Daudi (lane 3) cells with MBS617983 at 2 ug/ml.)
Western Blot (WB)
(Western Blot analysis of 30ug of total cell lysate from Jurkat (lane 1), HeLa (lane 2), and Daudi (lane 3) cells with MBS617983 at 2 ug/ml.)
Related Product Information for anti-DR6 antibody
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR6 (for death receptor 6)(1). The extracellular domain of DR6 contains four TNFR-like cysteine rich motifs that are related to those of osteoprotegerin (OPG)(2) and TNFR2(3) with 36% and 42% amino acid identities, respectively. The death domain of DR6 (amino acids 428-494) located adjacent to the transmembrane domain is most related to TNFR1 (27.2%) and least to DR5 (19.7%)(1).
Product Categories/Family for anti-DR6 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The DR6 dr6l (Catalog #AAA617983) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DR6 (Death Receptor6) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DR6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for the detection of DR6 expression by Western blot. Whole cell lysate from Jurkat, Daudi and HeLa cells can be used as positive control and approximately 66kD is detected. Western blot analysis of 30ug of total cell lysate from Jurkat (lane 1), HeLa (lane 2), and Daudi (lane 3) cells with antibody at 2ug/ml. Dilution: Western blot: 2-4ug/ml. Researchers should empirically determine the suitability of the DR6 dr6l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DR6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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