Goat DORFIN Polyclonal Antibody
DORFIN (E3 Ubiquitin-protein Ligase RNF19A, Double Ring-finger Protein, RING Finger Protein 19A, p38, RNF19A, RNF19)
Reactivity
Bovine, Canine, Human, Porcine
Applications
ELISA
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
DORFIN; Polyclonal Antibody; DORFIN (E3 Ubiquitin-protein Ligase RNF19A; Double Ring-finger Protein; RING Finger Protein 19A; p38; RNF19A; RNF19); Anti -DORFIN (E3 Ubiquitin-protein Ligase RNF19A; anti-DORFIN antibody
Host
Goat
Reactivity
Bovine, Canine, Human, Porcine
Clonality
Polyclonal
Specificity
Recognizes DORFIN. Species sequence homology: Bovine, canine, human and porcine.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Applicable Applications for anti-DORFIN antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Dilution: ELISA: 1:16,000
Dilution: ELISA: 1:16,000
Immunogen
Synthetic peptide corresponding to C-QTMELKVAIQTEI, from DORFIN, at C-terminal (NP_056250.3, NP_904355.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-DORFIN antibody
Dorfin is an E3 ubiquitin ligase which mediates ubiquitination of cellular proteins. Dorfin contains two RING-finger motifs and an IBR (in between RING fingers) motif. Dorfin interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. Dorfin is of interest in Parkinson's Disease, as it binds and ubiquitylates synphilin 1 (SNCAIP-interacts with alpha synuclein) in neurons. Furthermore, Dorfin expression is increased in Lewy bodies, the characteristic neuronal inclusions in Parkinson's diseased brains. In normal subjects, Dorfin is widely expressed at low levels with higher levels found in the heart and is ubiquitously expressed in the central nervous system. Alternatively spliced transcript variants encoding the same protein have been reported.
Product Categories/Family for anti-DORFIN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
dorfin
Similar Products
Product Notes
The DORFIN (Catalog #AAA6006602) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The DORFIN (E3 Ubiquitin-protein Ligase RNF19A, Double Ring-finger Protein, RING Finger Protein 19A, p38, RNF19A, RNF19) reacts with Bovine, Canine, Human, Porcine and may cross-react with other species as described in the data sheet. AAA Biotech's DORFIN can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: ELISA: 1:16,000. Researchers should empirically determine the suitability of the DORFIN for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DORFIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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