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Rabbit anti-Human Dopamine Receptor, D3, D3R Polyclonal Antibody

Dopamine Receptor, D3, D3R

Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified over the antigen-agarose column.
Synonyms
Dopamine Receptor; D3; D3R; Polyclonal Antibody; Anti -Dopamine Receptor; anti-Dopamine Receptor; D3R antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human Dopamine Receptor, D3. No significant sequence homology with other dopamine receptors (D1, D2, D4 or D5). Species sequence homology: monkey, 94%;
Purity/Purification
Affinity Purified
Purified over the antigen-agarose column.
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, 40% glycerol.
Applicable Applications for anti-Dopamine Receptor, D3, D3R antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1-10ug/ml. Using ECL
ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plates at 1ug/ml.
Immunohistochemistry: 2-10ug/ml
Immunogen
A synthetic peptide sequence of 19aa from the human D3 receptor within the 3rd cytoplasmic domain (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Dopamine Receptor, D3, D3R antibody
Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. DR have been classified into either the D1-like (D1, D1B, and D5) or D2-like (D2, D3, and D4). The two isoforms of D2R, D2 long (D2L) and short D2S), are encoded by splice variants of a single gene and differ only by the presence of an additional 29 AA in the intracellular domain 3 of the D2 long form. It may play a role in the coupling of the receptor to G- proteins. All members of this family have similar structure and contain 7 putative transmembrane domains. A given cell or tissue may express more than one DR. Specific radioligands do not exist that can differentiate between these DR. Therefore, specific antibodies are needed to distinguish, localize, and document changes in DR levels in cells and tissues under various normal and pathological conditions.
Product Categories/Family for anti-Dopamine Receptor, D3, D3R antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI Official Full Name
D3 dopamine receptor

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Product Notes

The Dopamine Receptor, D3, D3R (Catalog #AAA624239) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Dopamine Receptor, D3, D3R reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Dopamine Receptor, D3, D3R can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot and Immunohistochemistry. Dilution: Western Blot: 1-10ug/ml. Using ECL ELISA: 0.5-1ug/ml. Control peptide can be used to coat ELISA plates at 1ug/ml. Immunohistochemistry: 2-10ug/ml. Researchers should empirically determine the suitability of the Dopamine Receptor, D3, D3R for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dopamine Receptor, D3, D3R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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